Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
DNA-dependent RNA synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "DNA-dependent RNA synthesis" in MCE Product Catalog:
8
8 Publications Verification
Target:
Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
2
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
2
Target:
Research Areas:
Rifamycin (Rifamycin SV) is an orally active ansamycin antibiotic. Rifamycin inhibits DNA-dependent RNA synthesis. Rifamycin has antibacterial activity against Mycobacterium tuberculosis. Rifamycin interferes with hepatic bile acid metabolism. Rifamycin has anti-inflammatory effects. Rifamycin can be used in the study of Mycobacterium tuberculosis, Bacteroides fragilis infection, and Lipopolysaccharide (HY-D1056B3)-induced inflammation .
Cat. No.: HY-135184
CAS No.: 922717-97-3
Synonyms: CBR-2092; TNP-2092
Target:
Research Areas:
Rifaquizinone (CBR-2092; TNP-2092) is a rifamycin-quinolone hybrid antibiotic. Rifaquizinone has an IC50 of 0.034 μM against wild-type Staphylococcus aureus DNA-dependent RNA polymerase. Rifaquizinone potently inhibits Staphylococcus aureus infection, with an MIC range of 0.008-0.5 μg/mL against 300 clinical isolates of staphylococci and streptococci. Rifaquizinone can be used in research related to persistent Staphylococcus aureus infections .
Cat. No.: HY-13234R
CAS No.: 80621-81-4
Rifaximin (Standard) is the analytical standard of Rifaximin. This product is intended for research and analytical applications. Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
Cat. No.: HY-B1907R
CAS No.: 14897-39-3
Synonyms: Rifamycin SV sodium (Standard)
Target:
Cat. No.: HY-165401
CAS No.: 22785-18-8
Target:
Research Areas:
SC 19886 is an inhibitor of Aldosterone (HY-113313) synthesis. SC 19886 blocks Aldosterone-induced DNA-dependent RNA synthesis. SC 19886 can be used in studies related to primary aldosteronism [1] [2].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
