22785-18-8
22785-18-8
Chemical Structure
SC 19886
- CAS No.: 22785-18-8
- Formula:C19H26O2
- Molecular Weight:286.41
IUPAC Name: (6aS,6bS,10R,10aR,11aS,11bR)-10,11b-dimethyl-1,5,6,6a,6b,7,8,10,10a,11,11a,11b-dodecahydro-3H-benzo[a]fluorene-3,9(2H)-dione
InChIKey: QKJVUGLHJLJREL-WIDACUINSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@@]([C@H](C(CC4)=O)C)([H])C3
Biological Activity: SC 19886 is an inhibitor of Aldosterone (HY-113313) synthesis. SC 19886 blocks Aldosterone-induced DNA-dependent RNA synthesis. SC 19886 can be used in studies related to primary aldosteronism[1][2].
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SC 19886 | SC 19886 is an inhibitor of Aldosterone (HY-113313) synthesis. SC 19886 blocks Aldosterone-induced DNA-dependent RNA synthesis. SC 19886 can be used in studies related to primary aldosteronism. | |||||||||||||||||||||
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References
- [1]. Netchitailo P, et al. Relative inhibitory potency of five mineralocorticoid antagonists on aldosterone biosynthesis in vitro. Biochemical pharmacology. 1985 Jan 15;34(2):189-94. [Content Brief]
- [2]. Porter GA, et al. The effect of a new anti-aldosterone agent SC19886 on aldosterone-stimulated transepithelial sodium transport. J Steroid Biochem. 1972 Feb;3(2):201-8. [Content Brief]
Keywords
