Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Dilated Cardiomyopathy
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Dilated Cardiomyopathy" in MCE Product Catalog:
Cat. No.: HY-173117
Target:
Research Areas:
RA306 is an orally active CaMKIIδ/γ inhibitor with IC50 values of 15, 25, 61, and 420 nM against CaMKIIδ, γ, α, and β isoforms, respectively. RA306 reduces the serine/threonine phosphorylation level of PEAK1, inhibits PEAK1-mediated cancer cell migration and invasion, and attenuates the growth and metastasis of cancer xenografts. RA306 can be used in research related to triple-negative breast cancer and dilated cardiomyopathy .
Cat. No.: HY-P99047
CAS No.: 1318075-13-6
Synonyms: AB 0024; GS 6624
Target:
Research Areas:
Cat. No.: HY-175746
CAS No.: 3036141-78-0
Target:
Research Areas:
AZD0233 is an orally active CX3CR1 antagonist. AZD0233 modulates the CX3CR1/CX3CL1 signaling axis via immunomodulatory effects. AZD0233 has improved physicochemical properties, metabolic stability, low toxicity and CYP inhibition. AZD0233 improves cardiac function and reduces macrophages and fibrotic scar in mice model of dilated cardiomyopathy. AZD0233 can be used for cardiovascular diseases like dilated cardiomyopathy research .
Cat. No.: HY-19664
CAS No.: 99522-79-9
Synonyms: OPC-13340
Target:
Research Areas:
Pranidipine (OPC-13340) is an orally active L-type voltage-dependent calcium channel (L-VDCC) blocker with a Ki value of 0.16 nM. Pranidipine inhibits calcium-induced contraction, suppresses slow-response action potentials, shortens action potential duration, reduces systolic and diastolic blood pressure, and exerts vasodilatory effects. Pranidipine enhances its vasodilatory effect by blocking NO decomposition. Pranidipine can be used in research related to essential hypertension, angina pectoris, myocardial infarction, and dilated cardiomyopathy .
Cat. No.: HY-P10554
CAS No.: 171675-09-5
Target:
Research Areas:
Synonyms: PF-07265803; ARRY-797; ARRY-371797
Target:
Research Areas:
Emprumapimod (PF-07265803) is a potent, orally active and selective inhibitor of p38α MAPK directly inhibits LPS-induced IL-6 production from RPMI-8226 cell (IC50=100 pM). Emprumapimod can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
p38α inhibitor 1 (Arry-797) is a p38α inhibitor. p38α inhibitor 1 is applicable to research related to diseases including Alzheimer's disease and inflammatory dilated cardiomyopathy .
Cat. No.: HY-160846
CAS No.: 2653254-34-1
Target:
Research Areas:
HDAC6-IN-40 (Compound I-6) is an inhibitor for HDAC6 with IC50 of 0.029 μM .
Cat. No.: HY-120257
CAS No.: 204919-14-2
Research Areas:
IDN-1965 is an irreversible, broad-spectrum caspase inhibitor. IDN-1965 prevents downstream apoptotic events (such as DNase activation) and significantly delays cytochrome c release by inhibiting caspase activity. IDN-1965 significantly delayed death in mice with cardiomyocyte apoptosis. IDN-1965 completely prevents left ventricular dilation, systolic dysfunction, and fibrosis in mice with dilated cardiomyopathy. IDN-1965 can be used to study apoptosis-related diseases such as heart failure and the mechanisms of apoptosis initiation .
Cat. No.: HY-160845
CAS No.: 2653255-56-0
Target:
Research Areas:
HDAC6-IN-39 (Compound I-132) is an inhibitor for HDAC6 with IC50 of 0.0096 μM .
Cat. No.: HY-145564A
Purity: ≥98.0%
Synonyms: PF-07265803 hydrochloride; ARRY-797 hydrochloride; ARRY-371797 hydrochloride
Target:
Research Areas:
Emprumapimod (PF-07265803) hydrochloride is an orally active and selective inhibitor of p38α MAPK. Emprumapimod hydrochloride can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
Cat. No.: HY-P70006
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DES; CMD1I; Desmin; Cardiomyopathy, Dilated 1F (Autosomal Dominant); LGMD2R; Epididymis Secretory Sperm Binding Protein; CSM1; LGMD1D; CSM2; LGMD1E; Intermediate Filament Protein; CDCD3; Cardiomyopathy, Dilated 1I
Cat. No.: HY-P703646
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNNT2; Cardiac Muscle Troponin T; Prev. CMD1D; Troponin T Type 2 Cardiac; Prev. CMH2; Cardiac Troponin T; Troponin T, Cardiac Muscle; LVNC6; CMPD2; TnTC; Cardiomyopathy, Dilated 1D (Autosomal Dominant); RCM3; Cardiomyopathy, Hypertrophic 2; TnTc; Troponin
Cat. No.: HY-P71698
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TTN; Titin; EC 2.7.11.1; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14; SALMY; HMERF; EOMFC; CMYP5; CMYO5; TMD; CMH9; ; MYLK5 CMPD4; LGMDR10; LGMD2J; Transthyretin; Titin Fetal Isoform; Cardiomyopathy, Dilated 1G (Autosomal Dominant); CMD1G; FLJ32040
Cat. No.: HY-P82974
Synonyms: TNNT2; Cardiac muscle troponin T; Troponin T; cardiac muscle; troponin T type 2 (cardiac); Cardiac muscle troponin T antibody
Cardiomyopathy Dilated 1D (autosomal dominant) antibody;
Cardiomyopathy hypertrophic 2 antibody;
CMD1D antibody;
CMH2 antibody;
CMPD2 antibody;
cTnT antibody;
LVNC6 antibody;
MGC3889 antibody;
OTTHUMP00000033864 antibody;
RCM3 antibody;
TNNT 2 antibody;
TNNT2 antibody;
TNNT2_HUMAN antibody;
TnTc antibody;
Troponin T cardiac muscle antibody;
Troponin T2 cardiac antibody
Cat. No.: HY-P71469
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNNI3; Troponin I Type 3 (Cardiac); Prev. CMD2A; Troponin I Type 3; TNNC1; Mutant Cardiac Troponin I; Troponin I, Cardiac Muscle; Troponin I Type 3 Cardiac; CMH7; CMD1FF; CTNI; RCM1; Cardiomyopathy, Dilated 2A (Autosomal Recessive); Troponin I3, Cardiac T
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
