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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
EIF4A1
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "EIF4A1" in MCE Product Catalog:
3
Research Areas:
SBI-0640756 (SBI-756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex.
Cat. No.: HY-176842
CAS No.: 3083974-55-1
Research Areas:
eIF4A-IN-1 (Compound 79) is an eIF4A inhibitor that inhibits protein translation. eIF4A-IN-1 canb be used in gastric cancer research .
Cat. No.: HY-RS04270
Target:
Research Areas:
EIF4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176844
CAS No.: 3083978-00-8
Target:
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eIF4A-IN-1 intermediate (Compound 71E) is an intermediate of Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-1 intermediate can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-RS26657
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Eif4a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20153
Target:
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Eif4a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-129768
CAS No.: 2368900-33-6
Research Areas:
CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity .
Cat. No.: HY-RS04281
Target:
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EIF4G1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-145240
CAS No.: 2573979-31-2
eIF4E-IN-1 is a potent inhibitor of eIF4E. eIF4E-IN-1 inhibits immunosuppression components such as immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immune suppression in certain diseases, such as cancer and infectious disease (extracted from patent WO2021003194A1, compound Y) .
Cat. No.: HY-P701605
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A1; Eukaryotic Initiation Factor 4AI; Prev. EIF4A; EIF4A-I; DDX2A; Eukaryotic Translation Initiation Factor 4A, Isoform 1; EIF-4A; Eukaryotic Translation Initiation Factor 4A; ATP-Dependent RNA Helicase EIF4A-1; ATP-Dependent RNA Helicase; Eukaryotic
Cat. No.: HY-P701606
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A1; Eukaryotic Initiation Factor 4AI; Prev. EIF4A; EIF4A-I; DDX2A; Eukaryotic Translation Initiation Factor 4A, Isoform 1; EIF-4A; Eukaryotic Translation Initiation Factor 4A; ATP-Dependent RNA Helicase EIF4A-1; ATP-Dependent RNA Helicase; Eukaryotic
Cat. No.: HY-173172
CAS No.: 3076503-34-6
Research Areas:
MG-002 is an orally active eIF4A1 and eIF4A2 inhibitor with a human eIF4A1 IC50 of 43 nM. MG-002 prevents competent ribosome recruitment to mRNA, inhibits cap-dependent mRNA translation, and engages eIF4A2 via the same RNA clamping mechanism to inhibit mRNA translation. MG-002 induces G2/M cell cycle delay, induces apoptosis, suppresses synthesis of c-MYC and cyclin D1, and shows minimal overt toxicity in mice. MG-002 inhibits primary triple-negative breast cancer tumor growth, attenuates metastatic spread, and enhances anti-neoplastic activity of Doxorubicin (HY-15142A) in pre-clinical models .
Cat. No.: HY-RS04277
Target:
Research Areas:
EIF4EBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04280
Target:
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EIF4ENIF1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4ENIF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19254
Target:
Research Areas:
Eif4g1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4g1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20227
Target:
Research Areas:
Eif4ebp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25743
Target:
Research Areas:
Eif4g1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4g1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26734
Target:
Research Areas:
Eif4ebp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
