1. Cell Cycle/DNA Damage
  2. Eukaryotic Initiation Factor (eIF)
  3. CMLD012072

CMLD012072 

Cat. No.: HY-129768
Handling Instructions

CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity.

For research use only. We do not sell to patients.

CMLD012072 Chemical Structure

CMLD012072 Chemical Structure

CAS No. : 2368900-33-6

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Description

CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity[1].

IC50 & Target

eIF4A[1]

Molecular Weight

556.61

Formula

C₃₂H₃₂N₂O₇

CAS No.

2368900-33-6

SMILES

O[[email protected]]12[[email protected]](C(OC)=O)[[email protected]@H](C3=CC=CC=C3)[[email protected]]4(C5=CC=C(OC)C=C5)OC6=C(C(OC)=CC(OC)=C6)[[email protected]@]41NC(C7CC7)=N2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CMLD012072CMLD 012072CMLD-012072Eukaryotic Initiation Factor (eIF)Inhibitorinhibitorinhibit

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