2368900-33-6
Chemical Structure
CMLD012072
- CAS No.: 2368900-33-6
- Formula:C32H32N2O7
- Molecular Weight:556.61
IUPAC Name: methyl (3aR,4R,5S,5aR,10bR)-2-cyclopropyl-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-3a,4,5,5a-tetrahydro-1H-benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate
InChIKey: KAEUWSZLWVZGMK-GAFFYMCOSA-N
SMILES: O[C@]12[C@H](C(OC)=O)[C@@H](C3=CC=CC=C3)[C@]4(C5=CC=C(OC)C=C5)OC6=C(C(OC)=CC(OC)=C6)[C@@]41NC(C7CC7)=N2
Biological Activity: CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity[1].
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CMLD012072 | CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity. | |||||||||||||||||||||
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Keywords
