2. Search Result
Search Result
Results for "

ENO3

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N3415
    Kumatakenin
    1 Publications Verification

    		 Apoptosis Autophagy Caspase Ferroptosis SARS-CoV Neurological Disease Inflammation/Immunology Cancer
    Kumatakenin is an orally active apoptosis inducer and autophagy inhibitor, with a Kd value of 2.94 μM for mouse ATG5. Kumatakenin increases the activities of caspase-3, caspase-8 and caspase-9, thereby inducing caspase-dependent apoptosis in ovarian cancer cells. Kumatakenin reduces the expression of chemokines and pro-oncogenic factors in ovarian cancer cells, and inhibits M2 macrophage polarization. Kumatakenin inactivates TRIM65 function, reduces the expression and stability of FASN, and thus inhibits the proliferation, migration, invasion and tumor progression of esophageal cancer cells. Kumatakenin interacts with ATG5 to reduce its protein level, decrease LC3 level, and reduce the number of autophagosomes in the hippocampus. Kumatakenin binds to Eno3 to upregulate its expression, reduce the stability and expression level of IRP1 mRNA, inhibit ferroptosis, alleviate intestinal inflammation, and restore epithelial barrier function. Kumatakenin enhances the efficacy of antibiotics against pathogenic bacteria, inhibits SARS-CoV-2 replication, and reduces cytokine production. Kumatakenin is applicable to research related to ovarian cancer, esophageal cancer, depression and colitis [3] .
    Kumatakenin
  • HY-RS18474
    Eno3 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eno3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eno3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eno3 Mouse Pre-designed siRNA Set A
    Eno3 Mouse Pre-designed siRNA Set A
  • HY-RS04380
    ENO3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ENO3 Human Pre-designed siRNA Set A contains three designed siRNAs for ENO3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ENO3 Human Pre-designed siRNA Set A
    ENO3 Human Pre-designed siRNA Set A
  • HY-RS24955
    Eno3 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eno3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eno3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eno3 Rat Pre-designed siRNA Set A
    Eno3 Rat Pre-designed siRNA Set A

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: