2. Search Result
Search Result
Results for "

GADD45A

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Recombinant Proteins

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10587
    BIX-01294
    25+ Cited Publications

    		 Histone Methyltransferase Autophagy Cancer
    BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
    BIX-01294
  • HY-108239
    BIX-01294 trihydrochloride
    25+ Cited Publications

    		 Histone Methyltransferase Autophagy Cancer
    BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
    BIX-01294 trihydrochloride
  • HY-RS05229
    GADD45A Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GADD45A Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GADD45A Human Pre-designed siRNA Set A
    GADD45A Human Pre-designed siRNA Set A
  • HY-RS17861
    Gadd45a Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Gadd45a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gadd45a Mouse Pre-designed siRNA Set A
    Gadd45a Mouse Pre-designed siRNA Set A
  • HY-RS24330
    Gadd45a Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Gadd45a Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gadd45a Rat Pre-designed siRNA Set A
    Gadd45a Rat Pre-designed siRNA Set A
  • HY-10587R
    BIX-01294 (Standard)

    		Reference Standards Histone Methyltransferase Autophagy Cancer
    BIX-01294 (Standard) is the analytical standard of BIX-01294 (HY-10587). This product is intended for research and analytical applications. BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
    BIX-01294 (Standard)
  • HY-108239R
    BIX-01294 trihydrochloride (Standard)

    		Reference Standards Histone Methyltransferase Autophagy Cancer
    BIX-01294 trihydrochloride (Standard) is the analytical standard of BIX-01294 (trihydrochloride) (HY-108239). This product is intended for research and analytical applications. BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
    BIX-01294 trihydrochloride (Standard)
  • HY-136893
    SP-6-27

    		Microtubule/Tubulin Apoptosis Caspase Bcl-2 Family Cancer
    SP-6-27 is a tubulin depolymerizing agent that binds to the colchicine site of β-tubulin. SP-6-27 induces G2/M cell cycle arrest in ovarian cancer cells. SP-6-27 enhances intrinsic apoptosis in ovarian cancer cells through upregulation of Bax, Apaf-1, caspase-6, caspase-9, and caspase-3. SP-6-27 reduces ovarian cancer cell migration. SP-6-27 inhibits capillary tube formation by human umbilical vein endothelial cells. SP-6-27 shows minimum cytotoxicity to normal ovarian epithelia. SP-6-27 shows enhanced cytotoxicity in chemo-sensitive/resistant ovarian cancer cells when combined with Cisplatin (HY-17394). SP-6-27 can be used for the research of ovarian cancer .
    SP-6-27

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: