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Results for "

GN

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Peptides

1

Inhibitory Antibodies

1

Natural
Products

3

Recombinant Proteins

3

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-110266
    GN44028
    5+ Cited Publications

    		 HIF/HIF Prolyl-Hydroxylase Cancer
    GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers .
    GN44028
  • HY-117280
    GN25

    		MDM-2/p53 Cancer
    GN25 is a specific p53-Snail binding inhibitor with antitumor effects .
    GN25
  • HY-150177
    Mannose 6 phosphate

    		Drug Intermediate Metabolic Disease
    Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging .
    Mannose 6 phosphate
  • HY-P5309
    IgA1 Peptide GN5

    		Biochemical Assay Reagents Inflammation/Immunology
    IgA1 Peptide GN5 is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    IgA1 Peptide GN5
  • HY-P2082
    [D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH

    		GnRH Receptor Others
    [D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH is a gonadotropin-releasing hormone (Gn-RH) agonist that has a dose-dependent inhibitory activity on progesterone secretion from cultured human granulosa cells.
    [D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH
  • HY-P5309A
    IgA1 Peptide GN5 TFA

    		Biochemical Assay Reagents Inflammation/Immunology
    IgA1 Peptide GN5 (TFA) is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    IgA1 Peptide GN5 TFA
  • HY-163338
    Metallo-β-lactamase-IN-13

    		Beta-lactamase Infection
    Metallo-β-lactamase-IN-13 (Compound 13i) is a pan Metallo-β-Lactamase inhibitor. Metallo-β-lactamase-IN-13 provides broader coverage of metallo-β-lactamases expressing Gram-negative (GN) bacteria. Metallo-β-lactamase-IN-13 has antibacterial activity against P. aeruginosa .
    Metallo-β-lactamase-IN-13
  • HY-163339
    Metallo-β-lactamase-IN-14

    		Beta-lactamase Infection
    Metallo-β-lactamase-IN-14 (Compound 17e) is a Metallo-β-Lactamase inhibitor. Metallo-β-lactamase-IN-14 shows inhibition activity against VIM-1 and VIM-2. Metallo-β-lactamase-IN-14 has antibacterial activity against Gram-negative (GN) bacteria and P. aeruginosa .
    Metallo-β-lactamase-IN-14
  • HY-RS05568
    GNLY Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GNLY Human Pre-designed siRNA Set A contains three designed siRNAs for GNLY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GNLY Human Pre-designed siRNA Set A
    GNLY Human Pre-designed siRNA Set A
  • HY-183351
    GN-604

    		Cathepsin DNA/RNA Synthesis Autophagy Apoptosis Cancer
    GN-604 is a targeted drug conjugate (Targeted Drug Conjugate, TDC) formed by conjugation of GNS561 (HY-137978) with DN604, a Pt (II) complex. GN-604 selectively inhibits PPT1, induces lysosomal dysfunction, suppresses autophagy and triggers apoptosis. GN-604 promotes the targeted sequestration of Pt (II) inside cells, induces DNA damage and inhibits the proliferation of malignant cells. GN-604 is applicable to research related to triple-negative breast cancer .
    GN-604
  • HY-P11657
    GN-2 peptoid

    		Bacterial Infection
    GN-2 peptoid is a 9-mer cationic amphipathic peptoid and bactericidal agent with an overall net charge of +4, broad-spectrum antimicrobial activity, and low hemolytic and cytotoxic activity against mammalian cells. GN-2 peptoid exerts bactericidal action against Escherichia coli in a concentration-dependent manner. GN-2 peptoid exhibits antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, Pseudomonas aeruginosa strains. GN-2 peptoid shows low toxicity against human red blood cells and HeLa cells. GN-2 peptoid maintains antimicrobial activity in the presence of 50% human blood plasma. GN-2 peptoid can be used for the research of bacterial infections .
    GN-2 peptoid
  • HY-P991482
    ADI-42898

    		Influenza Virus Infection
    ADI-42898 is a human IgG1 monoclonal antibody (mAb) targeting Envelopment polyprotein, M polyprotein. ADI-42898 binds to the Gn/Gc complex and blocks the cell entry of seven HCPS- and HFRS-associated hantaviruses. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
    ADI-42898

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