3672-15-9
Chemical Structure
Mannose 6 phosphate
- CAS No.: 3672-15-9
- Formula:C6H13O9P
- Molecular Weight:260.14
IUPAC Name: 8-bromo-6-methoxyquinoline-3-carboxylic acid
InChIKey: VFRROHXSMXFLSN-KVTDHHQDSA-N
SMILES: O=C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Biological Activity: Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging[1][2].
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Mannose 6 phosphate | Mannose 6 phosphate is an essential precursor for mannosyl glycoconjugates, including lipid-linked oligosaccharides (LLO; glucose3mannose9GlcNAc2-P-P-dolichol) used for protein N-glycosylation. Mannose 6 phosphate causes specific LLO cleavage. Mannose 6 phosphate causes specific degradation of G3M9Gn2-P-P-Dol. Complexes containing Mannose 6 phosphate can remodel the dermal collagen network, improve skin biomechanical properties, and reverse visible signs of aging. Mannose 6 phosphate can be used in research related to skin aging. | |||||||||||||||||||||
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References
- [1]. Gao N, et al. Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides. Mol Biol Cell. 2011 Sep;22(17):2994-3009. [Content Brief]
- [2]. Meunier M, et al. Mannose-6-phosphate complex and improvement in biomechanical properties of the skin. J Cosmet Dermatol. 2021;20(6):1598-1610. [Content Brief]
