1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase
  3. GN44028

GN44028 

Cat. No.: HY-110266 Purity: >99.0%
Handling Instructions

GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.

For research use only. We do not sell to patients.

GN44028 Chemical Structure

GN44028 Chemical Structure

CAS No. : 1421448-26-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 308 In-stock
Estimated Time of Arrival: December 31
5 mg USD 280 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Description

GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization[1].

IC50 & Target

IC50: 14 nM (HIF-1)[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

305.33

Formula

C₁₈H₁₅N₃O₂

CAS No.

1421448-26-1

SMILES

C1(NC2=CC=C(OCCO3)C3=C2)=NNC4=C1CC5=CC=CC=C45

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >99.0%

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Product Name:
GN44028
Cat. No.:
HY-110266
Quantity:

GN44028

Cat. No.: HY-110266