16 Results for "

GalR

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "GalR" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1127
CAS No.: 119418-04-1
Synonyms: Glanin
Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.
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Cat. No.: HY-P1130
CAS No.: 908844-75-7
Synonyms: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide
M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is an orally active and selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM, 420 nM and >10 μM for GalR2, GalR1 and GalR3 respectively. M871 relieves the mice allergic rhinitis by reducing IgE production, as well as the number of B cells in tissues. M871 can inhibit the nerve invasion of salivary adenoid cystic carcinoma (SACC) and alleviate myocardial ischemia-reperfusion injury. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain) .
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Cat. No.: HY-123671
CAS No.: 1308833-36-4
Purity:  96.01%
Research Areas:  

Neurological Disease

CYM2503 is a putative GalR2-positive allosteric modulator. CYM2503 increases the latency to first electrographic seizure and decreases the total time in seizure. CYM2503 also attenuates electroshock-induced seizures in mice. Galanin receptors type 1 (GalR1) and/or type 2 (GalR2) represent unique pharmacological targets for the research of seizures and epilepsy .
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Cat. No.: HY-P1135
CAS No.: 1172089-00-7
Research Areas:  

Neurological Disease

M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin .
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Cat. No.: HY-P5894
Synonyms: Galanin-like peptide (3-32)
Research Areas:  

Neurological Disease

human GALP (3-32) (Galanin-like peptide (3-32)) is a potent galanin receptor agonist with high affinity for both GalR1 (IC50=33 nM) and GalR2 (IC50=15 nM) in a competitive binding study. human GALP (3-32) exhibits the high potency in altering the extracellular acidification rate of SH-SY5Y cells transfected with GalR2 (EC50=360 nM) .
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Cat. No.: HY-RS05264
Research Areas:  

Others

GALR1 Human Pre-designed siRNA Set A contains three designed siRNAs for GALR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05265
Research Areas:  

Others

GALR2 Human Pre-designed siRNA Set A contains three designed siRNAs for GALR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05266
Research Areas:  

Others

GALR3 Human Pre-designed siRNA Set A contains three designed siRNAs for GALR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS20934
Research Areas:  

Others

Galr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Galr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS22523
Research Areas:  

Others

Galr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Galr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1129
CAS No.: 367518-31-8
Research Areas:  

Neurological Disease

AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain .
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Cat. No.: HY-P5064
CAS No.: 245114-96-9
Research Areas:  

Neurological Disease

Galanin-Like Peptide (porcine) is a 60 amino acid neuropeptide that was first isolated from the porcine hypothalamus. Galanin-Like Peptide (porcine) has a high affinity for the GALR2 receptor (IC50 of 0.24 nM) and a lower affinity for the GALR1 receptor (IC50 of 4.3 nM) .
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Cat. No.: HY-P1135A
Research Areas:  

Neurological Disease

M1145 TFA, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 TFA shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 TFA has an additive effect on the signal transduction of galanin .
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Cat. No.: HY-RS27451
Research Areas:  

Others

Galr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Galr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-RS29044
Research Areas:  

Others

Galr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Galr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-W415856
CAS No.: 7296-64-2
Synonyms: Beta-D-galactose
Target:  

Drug Derivative

Research Areas:  

Others

β-D-galactose (Beta-D-galactose) is one of the two anomers of D-Galactose (HY-N0210). β-D-galactose efficiently binds to and inhibits the galactose repressor (GalR), thereby inducing the expression of the gal regulon. β-D-galactose acts as a persistent induction signal to trigger the synthesis of UDP-galactose for the biosynthetic glycosylation pathway, rather than serving as a carbon source in Yersinia pestis with inactivated GalM .
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