1172089-00-7
1172089-00-7
Chemical Structure
M1145
- CAS No.: 1172089-00-7
- Formula:C128H205N37O32
- Molecular Weight:2774.23
SMILES: [RGRGNWTLNSAGYLLGPVLPPPALALA-NH2]
Biological Activity: M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin[1].
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M1145 | 99.96% | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin. | ||||||||||||||||||||
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References
Keywords
