4 Results for "

Ganoderic acid H

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Ganoderic acid H" in MCE Product Catalog:

Cat. No.: HY-N1513
CAS No.: 98665-19-1
Ganoderic acid H is a hydroxylated lanostane-type triterpenoid derived from Ganoderma lucidum with anticancer activity. Ganoderic acid H inhibits the constitutive transactivation activity of AP-1 and NF-κB; it also downregulates the secretion of uPA and the expression of CDK4, and suppresses the growth, adhesion, migration and invasion of cancer cells. Ganoderic acid H inhibits HIV-1 protease in vitro. Ganoderic acid H can be used in studies related to breast cancer and HIV infection .
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Cat. No.: HY-129150
CAS No.: 862893-75-2
Purity:  ≥98.0%
Ganoderic acid TR is a broad-spectrum inhibitor of influenza neuraminidase enzymes (NAs). Ganoderic acid TR has IC50 values of 10.9 and 4.6 μM for H5N1 and H1N1 NAs, respectively. Ganoderic acid TR is limited by cytotoxicity and shows only weak activity against Oseltamivir (HY-13317)-resistant H1N1 viruses and influenza B viruses .
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Cat. No.: HY-129152
CAS No.: 112430-64-5
Target:  

Influenza Virus

Research Areas:  

Infection

Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM) .
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Cat. No.: HY-N11646
CAS No.: 1421611-59-7
Target:  

Bacterial

Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .
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