112430-64-5
Chemical Structure
Ganoderic acid T-N
- CAS No.: 112430-64-5
- Formula:C32H48O5
- Molecular Weight:512.72
IUPAC Name: (R,E)-6-((3S,5R,10S,13R,14R,15S,17R)-15-acetoxy-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylhept-2-enoic acid
InChIKey: YCWGPALSXRBKTM-FKJOTFDOSA-N
SMILES: C[C@]12C3=CC[C@](C(C)([C@H](CC4)O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@@](C[C@@H]2OC(C)=O)([H])[C@H](C)CC/C=C(C)/C(O)=O)C
Biological Activity: Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].
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Ganoderic acid T-N | Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM). | |||||||||||||||||||||
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Keywords
