Ganoderic acid T-N
Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM).
For research use only. We do not sell to patients.
- CAS No.: 112430-64-5
- Formula: C32H48O5
- Molecular Weight:512.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | IC50 |
25 μM
Compound: 18
|
Inhibition of topoisomerase 2a in human HuH7 cells
Inhibition of topoisomerase 2a in human HuH7 cells
|
[PMID: 23092389] |
| Huh-7 | IC50 |
55 μM
Compound: 18
|
Inhibition of topoisomerase 1 in human HuH7 cells
Inhibition of topoisomerase 1 in human HuH7 cells
|
[PMID: 23092389] |
Chemical Information
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CAS No. 112430-64-5
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Molecular Weight 512.72
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Formula C32H48O5
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SMILES
C[C@]12C3=CC[C@](C(C)([C@H](CC4)O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@@](C[C@@H]2OC(C)=O)([H])[C@H](C)CC/C=C(C)/C(O)=O)C
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Initial Source
Ganoderma lingzhi
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)