13 Results for "

Geranylgeranyl Diphosphate

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Geranylgeranyl Diphosphate" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113037C
CAS No.: 116057-57-9
Purity:  ≥95.0%
Synonyms: Farnesyl Diphosphate ammonium
Farnesyl pyrophosphate (Farnesyl diphosphate) ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases .
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Cat. No.: HY-113037
CAS No.: 13058-04-3
Synonyms: (E/Z)-Farnesyl Diphosphate
(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
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Cat. No.: HY-113037CS
Synonyms: Farnesyl Diphosphate-d2 triammonium
Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
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Cat. No.: HY-113752
CAS No.: 902630-14-2
Purity:  99.54%
Target:  

Parasite

Research Areas:  

Infection

MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 µM. MMV019313 has activity against P. falciparum (Parasite) .
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Cat. No.: HY-111636
Target:  

Apoptosis

Research Areas:  

Cancer

VSW1198 is an inhibitor for geranylgeranyl diphosphate synthase (GGDPS) with an IC50 of 45 nM. VSW1198 reveals antitumor activity in myeloma- and prostate cancer with liver toxicity .
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Cat. No.: HY-124723
CAS No.: 627545-07-7
Gerfelin inhibits geranylgeranyl diphosphate synthase (GGPP synthase) activity with an IC50 of 3.5 μg/mL .
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Cat. No.: HY-113869
CAS No.: 1059677-40-5
Target:  

Apoptosis PI3K Akt

Research Areas:  

Cancer

BPH-628 is an aromatic geranylgeranyl diphosphate synthase (GGPPS) inhibitor, with a pIC50 of 6.1 .
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Cat. No.: HY-113793
CAS No.: 1059677-12-1
Target:  

Ras

Research Areas:  

Cancer

BPH-742 (compound 9) is a Geranylgeranyl diphosphate synthase inhibitor with IC50 of 0.1 μM. BPH-742 has antitumor activity .
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Cat. No.: HY-163334
Target:  

Ras

Research Areas:  

Cancer

GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC50 of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells .
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Cat. No.: HY-136829
CAS No.: 946417-21-6
Target:  

Apoptosis

Research Areas:  

Others

BPH-675 is a large bisphosphonate inhibitor with long hydrophobic side chains and a potent and selective geranylgeranyl diphosphate synthase (GGPPS) inhibitor with an IC50 of 0.71 μM. GGPPS inhibitor promotes HUVEC apoptosis .
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Cat. No.: HY-P70224
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGPS1; GGPPS1; Geranylgeranyl Diphosphate Synthase 1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; (2E,6E)-Farnesyl Diphosphate Synthase; GGPPSase; Dimethylallyltranstransferase; MUDHLOV; Farnesyl Diphosphate
Species:  
Source:  
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Cat. No.: HY-P702577
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGPS1; GGPPS1; Geranylgeranyl Diphosphate Synthase 1; Geranylgeranyl Diphosphate Synthase; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; (2E,6E)-Farnesyl Diphosphate Synthase; GGPPSase; Dimethylallyltranstransferase; MUDHLOV; Farnesyl Diphosphate
Species:  
Source:  
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Cat. No.: HY-126472
CAS No.: 2809-23-6
Target:  

Farnesyl Transferase

Research Areas:  

Cancer

BPH252 (Compound 4) is a geranylgeranyl diphosphate synthase inhibitor. BPH252 can be used in research on bisphosphonate-based anticancer inhibitors .
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