11 Results for "

HJV

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "HJV" in MCE Product Catalog:

Cat. No.: HY-147278
CAS No.: 2646704-10-9
Synonyms: Divesiran; SLN124
Manusiran (Divesiran) is a GalNac-siRNA targeting liver and transmembrane serine protease 6 (Serine protease 6). Manusiran increases hepatic Hepcidin synthesis and plasma levels by silencing TMPRSS6, a negative regulator of hepcidin production, and limits the availability of iron required for erythropoiesis. Combined use of Manusiran with Deferiprone (HY-B0568) reduces ineffective erythropoiesis and hepatic iron overload in a mouse model of β-thalassemia. Manusiran can be used for research on polycythemia vera, type 1 hereditary hemochromatosis, and β-thalassemia .
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Cat. No.: HY-RS06191
Research Areas:  

Others

HJV Human Pre-designed siRNA Set A contains three designed siRNAs for HJV gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25075
Research Areas:  

Others

Hjv Rat Pre-designed siRNA Set A contains three designed siRNAs for Hjv gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-147278A
Synonyms: Divesiran sodium; SLN124 sodium
Manusiran sodium (Divesiran sodium) is a GalNac-siRNA targeting liver and transmembrane serine protease 6 (Serine protease 6). Manusiran sodium increases hepatic Hepcidin synthesis and plasma levels by silencing TMPRSS6, a negative regulator of hepcidin production, and limits the availability of iron required for erythropoiesis. Combined use of Manusiran sodium with Deferiprone (HY-B0568) reduces ineffective erythropoiesis and hepatic iron overload in a mouse model of β-thalassemia. Manusiran sodium can be used for research on polycythemia vera, type 1 hereditary hemochromatosis, and β-thalassemia .
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Cat. No.: HY-P991637
CAS No.: 2996101-49-4
Synonyms: REGN7999

Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

REGN7999 is a monoclonal antibody that inhibits TMPRSS6. REGN7999 inhibits TMPRSS6 activity, preventing Hemojuvelin (HJV) lysis, thereby enhancing BMP6-HJV signaling and increasing serum hepcidin. REGN7999 ameliorates iron overload and impaired erythropoiesis in a β-thalassemia mouse model by inhibiting TMPRSS6 activity. REGN7999 is indicated for research in β-thalassemia .
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Cat. No.: HY-RS18590
Research Areas:  

Others

Hjv Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hjv gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P78029
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
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Source:  
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Cat. No.: HY-P78028
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
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Cat. No.: HY-P701035
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
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Cat. No.: HY-P703949
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
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Source:  
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Cat. No.: HY-P703961
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
Species:  
Source:  
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