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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
HWP1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "HWP1" in MCE Product Catalog:
Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect [1].
Cat. No.: HY-B1237
CAS No.: 54767-75-8
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Suloctidil is an orally active calcium channel blocker and antifungal agent. Suloctidil antagonizes vasoconstriction induced by norepinephrine, angiotensin and serotonin. Suloctidil inhibits platelet function and exhibits neuroprotective effects. Suloctidil exerts inhibitory effects on Candida albicans biofilm and virulence. Suloctidil can be used in research on vasospasm relief, antithrombosis and superficial candidiasis [1] .
Cat. No.: HY-178732
CAS No.: 1463913-43-0
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AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis [1].
Cat. No.: HY-N11772
CAS No.: 875455-92-8
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Cat. No.: HY-184728
Antifungal agent-169 (compound 5p) is an antifungal agent that inhibits fluconazole (HY-B0101)-susceptible Candida albicans SC5314 with an MIC50 of 0.28 μM. Antifungal agent-169 reduces the expression levels of cAMP-PKA pathway-related genes including RAS1, EFG1, BCR1, ECE1 and HWP1 in Candida albicans. Antifungal agent-169 inhibits biofilm formation and hyphal growth of Candida albicans. Antifungal agent-169 can be used in studies related to Candida albicans infection [1].
Cat. No.: HY-N11772R
CAS No.: 875455-92-8
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Cat. No.: HY-126443A
CAS No.: 1352296-65-1
Antifungal agent 173 is an orally active antifungal (fungal) agent. Antifungal agent 173 disrupts fungal cell membrane integrity, inhibits yeast-hypha transition in Candida species, and suppresses biofilms. Antifungal agent 173 prevents mouse mortality in a mouse model of systemic candidiasis and reduces tongue lesions in a mouse model of oropharyngeal candidiasis. Antifungal agent 173 is applicable to research related to candidiasis [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
