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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
HsNmt1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "HsNmt1" in MCE Product Catalog:
9
9 Cited Publications
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Research Areas:
IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a Kd of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection [1].
Cat. No.: HY-160945
CAS No.: 3032302-70-5
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NMT-IN-7 is a N-myristoyl transferase (NMT) inhibitor, with IC50s of 2.1 nM for HsNMT1M, 0.6 nM for SU-DHL-10 cell. NMT-IN-7 can be used as a ADC cytotoxin [1].
Cat. No.: HY-171814
CAS No.: 3032302-82-9
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Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 is an drug-linker conjugate for ADC that contains a potent NMT inhibitor (NMT-IN-7), with an IC50 of 2.1 nM against HsNMT1. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 consists of an NMT inhibitor (HY-160945) and a stable cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 can be used for ADC synthesis and breast cancer-related research [1].\n
Cat. No.: HY-RS09389
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NMT1 Human Pre-designed siRNA Set A contains three designed siRNAs for NMT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183872
CAS No.: 851075-79-1
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FTR1335 is an Antifungal agent as well as a selective, substrate peptide-competitive, and myristoyl-CoA non-competitive inhibitor of N-myristoyltransferase CaNmt, with an IC50 of 0.49 nM against Candida albicans CaNmt. FTR1335 exhibits fungicidal activity against Candida albicans and inhibits the growth of Candida tropicalis. FTR1335 can be used in research related to Candida albicans infections [1] .
Cat. No.: HY-134199
CAS No.: 2059148-58-0
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IMP-1002 is a Plasmodium N-myristoyltransferase (NMT) inhibitor. IMP-1002 inhibits myristoylation activity, blocks parasite development. IMP-1002 can be used for the research of malaria [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
