3032302-82-9
Chemical Structure
Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7
- CAS No.: 3032302-82-9
- Formula:C55H66F2N8O17
- Molecular Weight:1149.15
InChIKey: XYCHGCXVVIRNGK-GKTBLRDKSA-N
SMILES: O=C(C=CC1=O)N1CCOCCOCCC(NCCC(NC(C=C2COC(N(C)CC3=CN=C4N3C=C(C5=C(C(F)=C(C=C5)F)OCCC6=C(C)N(C)N=C6C(O)C(C)(C)C)C=C4)=O)=C(C=C2)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(O)=O)=O)=O
Biological Activity:
Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 is an drug-linker conjugate for ADC that contains a potent NMT inhibitor (NMT-IN-7), with an IC50 of 2.1 nM against HsNMT1. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 consists of an NMT inhibitor (HY-160945) and a stable cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 can be used for ADC synthesis and breast cancer-related research[1].\n
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 | 95.42% | Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 is an drug-linker conjugate for ADC that contains a potent NMT inhibitor (NMT-IN-7), with an IC50 of 2.1 nM against HsNMT1. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 consists of an NMT inhibitor (HY-160945) and a stable cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide)-NMT-IN-7 can be used for ADC synthesis and breast cancer-related research.\n |
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