26 Results for "

Hydroxy-PEG2-CH2COOH

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Hydroxy-PEG2-CH2COOH" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Cat. No.: HY-125586
CAS No.: 21150-22-1
Purity:  ≥96.0%
Research Areas:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-172320
CAS No.: 2919596-13-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-986238 is an orally active macrocyclic peptide PD-L1 inhibitor. BMS-986238 can be used in the research of tumors such as solid tumors and lymphomas .
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Cat. No.: HY-P10392AF
Target:  

Wnt β-catenin

Research Areas:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
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Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
Target:  

Phospholipase Fungal

Research Areas:  

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
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Cat. No.: HY-140497
CAS No.: 51951-04-3
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Hydroxy-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-P10224A
Target:  

EGFR

Research Areas:  

Cancer

G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .
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Cat. No.: HY-P10896
CAS No.: 1446005-10-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
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Cat. No.: HY-P4755
CAS No.: 282726-24-3
Research Areas:  

Others

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide composed of L-phenyleline and L-leucine bound to aniline groups. N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide can be used to quantitatively determine the N-terminal heme adduct formed upon exposure to propylene oxide (PO) .
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Cat. No.: HY-P3100
CAS No.: 939960-34-6
Target:  

Parasite

Research Areas:  

Infection

Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
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Cat. No.: HY-P10964
CAS No.: 2802416-72-2
Target:  

GHSR

Research Areas:  

Endocrinology

Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .
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Cat. No.: HY-125357
CAS No.: 148619-41-4
Target:  

Peptides

Research Areas:  

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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Cat. No.: HY-158104
Target:  

ATF6

Research Areas:  

Others

LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers .
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Cat. No.: HY-P10224
CAS No.: 936728-13-1
Target:  

EGFR

Research Areas:  

Cancer

G7-18NATE is a peptide inhibitor of Grb7. HY-P10224 binds to the Grb7-SH2 domain with micromolar affinity (KD = 18.1 μM). G7-18NATE inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .
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Cat. No.: HY-P5568
CAS No.: 152835-17-1
Synonyms: RP 71955
Target:  

HIV

Research Areas:  

Infection

RP 71955 is an antimicrobial peptide against HIV-1 .
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Cat. No.: HY-P11625
Target:  

RXFP Receptor

Research Areas:  

Cardiovascular Disease

R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
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Cat. No.: HY-P11783
CAS No.: 86711-55-9
Target:  

Fungal

Research Areas:  

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
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