Plipastatin A1  (Synonyms: Fengycin IX; SNA-60-367-3)

Plipastatin A1 is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold^[1][2].

Plipastatin A1 (1-50 μM; 12-24 h) significantly inhibits Botrytis cinerea conidia germination in vitro at concentrations ≥1 μM after 12 h, and at concentrations ≥10 μM after 24 h^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Plipastatin A1 (50 μM; topical application; single dose) significantly reduces the spread of gray mold disease lesions on tomato leaf discs inoculated with Botrytis cinerea^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1463.71

C₇₂H₁₁₀N₁₂O₂₀

103651-09-8

{(3R)-3-hydroxy-1-oxohexadecyl}-Glu-{d-Orn}-Tyr-{d-Thr}-Glu-{d-Ala}-Pro-Gln-{d-Tyr}-Ile (Lactam bridge: Tyr3-Ile10)

{(3R)-3-hydroxy-1-oxohexadecyl}-E-{d-Orn}-Y{d-Thr}-E-{d-Ala}-PQ{d-Tyr}-I (Lactam bridge: Tyr3-Ile10)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Honma M, et al. Termination of the structural confusion between plipastatin A1 and fengycin IX. Bioorg Med Chem. 2012;20(12):3793-3798.  [Content Brief]

  [2]. Ma Z, et al. Plipastatin A1 produced by a marine sediment-derived Bacillus amyloliquefaciens SH-B74 contributes to the control of gray mold disease in tomato. 3 Biotech. 2018 Feb;8(2):125.  [Content Brief]