10 Results for "

Hypnotic effect

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Hypnotic effect" in MCE Product Catalog:

Cat. No.: HY-B0971
CAS No.: 132-20-7
Synonyms: Prophenpyridamine maleate; Tripoton maleate
Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
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Cat. No.: HY-150334
CAS No.: 50330-59-1
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Rilmazolam is a metabolite of Rilmazafone (HY-106547) and hypnotic agent. Rilmazolam exerts a significant sleep-inducing effect. Rilmazolam can be used in insomnia-related research .
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Cat. No.: HY-B0971A
CAS No.: 86-21-5
Synonyms: Prophenpyridamine; Tripoton; Pheniramine solution
Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
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Cat. No.: HY-169432
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

TET-13 is a positive allosteric modulator of GABAA receptor with an EC50 of 5.65 μM, lower than that of Etomidate (EC50: 9.29 μM). TET-13 shows potent anesthetic effects in both mice and rats (ED50: 0.48 mg/kg and 0.69 mg/kg, respectively) .
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Cat. No.: HY-163978
CAS No.: 1350113-04-0
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

YGZ-331 is a sedative with a calming effect. YGZ-331 is a derivative of the adenosine nucleoside NGBA, which can increase GABA levels. YGZ-331 exerts a sedative-hypnotic effect by activating A1R and A2aR, and inhibiting CaMKII phosphorylation (pCaMKII) levels. YGZ-331 can reduce the spontaneous motor activity of mice .
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Cat. No.: HY-B0971AR
CAS No.: 86-21-5
Synonyms: Prophenpyridamine (Standard); Tripoton (Standard); Pheniramine solution (Standard)
Pheniramine (Standard) is the analytical standard of Pheniramine. This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
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Cat. No.: HY-B0971R
CAS No.: 132-20-7
Synonyms: Prophenpyridamine maleate (Standard); Tripoton maleate (Standard); Pheniramine maleate (Standard)
Pheniramine (maleate) (Standard) is the analytical standard of Pheniramine (maleate). This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .
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Cat. No.: HY-115861
CAS No.: 944284-77-9
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

UCM765 is a selective MT2-type melatonin receptor ligand with hypnotic, analgesic and anxiolytic activities. The partial agonist effect of UCM765 has attracted attention in pharmacological studies. By structurally modifying UCM765, its water solubility and metabolic stability can be improved, thereby increasing its bioavailability. The biological activity of UCM765 has been verified in a rat model, supporting its potential for further pharmacological studies .
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Cat. No.: HY-162620
CAS No.: 2971825-58-6
Target:  

Adrenergic Receptor

Research Areas:  

Cancer

α2A-AR agonist 1 (Compound B9) is a selective agonist for α2-adrenergic receptor (α2A-AR) with EC50 of 0.23 nM. α2A-AR agonist 1 exhibits a hypnotic effect, with ED50 of 0.138 mg/kg in the loss of righting reflex (LORR) experiment. α2A-AR agonist 1 exhibits metabolic stability in mouse liver microsomes .
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Cat. No.: HY-N13715
CAS No.: 16408-77-8
Thalicminine is an alkaloid, which is found in Thalictrum species. Thalicminine can cause respiratory stimulation and a brief hypotensive effect on dogs. Thalicminine also prolongs the hypnotic effect of Chloral hydrate in mice .
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