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Results for "

ILT3 (LILRB4)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LILRB (3) Transmembrane Glycoprotein (2)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: LILRB Human leukocyte immunoglobulin (Ig)-like receptors (LILR)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991307

BND-35	LILRB Transmembrane Glycoprotein	Cancer
BND-35 is a human monoclonal antibody (mAb) targeting *LILRB4/ILT3/CD85k. BND-35 blocks the interaction of ILT3* with APOE and fibronectin, enhances the pro-inflammatory activity of various myeloid cells, and reverses ILT3-mediated immunosuppression of T cells by various suppressive myeloid cells. BND-35 has anti-tumor activity in the hILT3 transgenic mouse tumor model .

HY-P991308

TRX385	LILRB Transmembrane Glycoprotein	Infection Cancer
TRX385 is a human monoclonal antibody (mAb) targeting *LILRB4/ILT3/CD85k*. TRX385 can be used in anticancer and antiviral research .

HY-P992389

IO-202	LILRB	Cancer
IO-202 is a high-affinity *LILRB4/ILT3* binder and myeloid checkpoint inhibitor. IO-202 blocks APOE binding and LILRB4 activation to reverse T-cell suppression and enhance T-cell cytotoxicity, while eliminating LILRB4-high-expressing leukemic blasts via ADCC and ADCP mechanisms. IO-202 promotes dendritic cell maturation and antigen presentation, reshapes the phenotype of tumor-associated macrophages, and reduces myeloid-derived suppressor cells. IO-202 is widely applicable to research on relapsed/refractory acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML), and solid tumors ^[3].

Cat. No.	Product Name	Target	Research Area	Image

HY-P990462

*Anti-LILRB4/ILT3/CD85k Antibody*	Inhibitory Antibodies	Inflammation/Immunology
Anti-LILRB4/ILT3/CD85k Antibody is a CHO-expressed humanized antibody that targets *LILRB4/ILT3/CD85k. The predicted molecular weight (MW) of Anti-LILRB4/ILT3/CD85k* Antibody is 144.36 kDa.

HY-P991307

BND-35	LILRB Transmembrane Glycoprotein	Cancer
BND-35 is a human monoclonal antibody (mAb) targeting *LILRB4/ILT3/CD85k. BND-35 blocks the interaction of ILT3* with APOE and fibronectin, enhances the pro-inflammatory activity of various myeloid cells, and reverses ILT3-mediated immunosuppression of T cells by various suppressive myeloid cells. BND-35 has anti-tumor activity in the hILT3 transgenic mouse tumor model .

HY-P991308

TRX385	LILRB Transmembrane Glycoprotein	Infection Cancer
TRX385 is a human monoclonal antibody (mAb) targeting *LILRB4/ILT3/CD85k*. TRX385 can be used in anticancer and antiviral research .

HY-P992389

IO-202	LILRB	Cancer
IO-202 is a high-affinity *LILRB4/ILT3* binder and myeloid checkpoint inhibitor. IO-202 blocks APOE binding and LILRB4 activation to reverse T-cell suppression and enhance T-cell cytotoxicity, while eliminating LILRB4-high-expressing leukemic blasts via ADCC and ADCP mechanisms. IO-202 promotes dendritic cell maturation and antigen presentation, reshapes the phenotype of tumor-associated macrophages, and reduces myeloid-derived suppressor cells. IO-202 is widely applicable to research on relapsed/refractory acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML), and solid tumors ^[3].

Species:	Human (14) Mouse (3) Cynomolgus (2)
Tag:	His (13) Avi (9) Fc (6)
Source:	HEK293 (19)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P77738

	LILRB4/CD85k/ILT3 Protein, Cynomolgus (HEK293, His) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Cynomolgus	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704249

	LILRB4/CD85k/ILT3 Protein, Cynomolgus (HEK293, Fc) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Cynomolgus	HEK293
	LILRB4/CD85k/ILT3 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293, with C-hFc tag.

HY-P704762

	LILRB4/CD85k/ILT3 Protein, Human (HEK293, mFc) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	LILRB4/CD85k/ILT3 Protein, Human (HEK293, mFc) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293, with C-mFc tag.

HY-P77743

	LILRB4/CD85k/ILT3 Protein, Human (HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. LILRB4/CD85k/ILT3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P77744

	LILRB4/CD85k/ILT3 Protein, Human (Biotinylated, HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. LILRB4/CD85k/ILT3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P705056

	LILRB4/CD85k/ILT3 Protein, Human (Biotinylated, HEK293, Fc-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293

HY-P701065

	LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human (HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human (HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 Domain 1+hinge protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700780

	LILRB4/CD85k/ILT3 Domain 1 Protein, Human (HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Domain 1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P701064

	LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human (Biotinylated, HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 Domain 1+hinge protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P700779

	LILRB4/CD85k/ILT3 Domain 1 Protein, Human (Biotinylated, HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Domain 1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P701018

	LILRB4/CD85k/ILT3 Domain 2 Protein, Human (Biotinylated, HEK293, His-Avi) HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Domain 2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78645

	*FITC-Labeled LILRB4/CD85k/ILT3* Protein, Human (HEK293, His)** LILRB4; ILT3; LIR5; CD85K; HM18	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. FITC-Labeled LILRB4/CD85k/ILT3 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78646

	*FITC-Labeled LILRB4/CD85k/ILT3* Protein, Human (HEK293, Fc)** LILRB4; ILT3; LIR5; CD85K; HM18	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. FITC-Labeled LILRB4/CD85k/ILT3 Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72519

	LILRB4/CD85k/ILT3 Protein, Human (HEK293, His) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. LILRB4/CD85k/ILT3 Protein, Human (HEK293, His) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76441

	LILRB4/CD85k/ILT3 Protein, Human (HEK293, hFc) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Human	HEK293
	LILRB4 is a leukocyte immunoglobulin-like receptor located on chromosome 19q13.4 and has an extracellular immunoglobulin domain, a transmembrane domain and a cytoplasmic ITIM. It is expressed on immune cells, interacts with class I MHC, and inhibits the stimulation of immune responses. LILRB4/CD85k/ILT3 Protein, Human (HEK293, hFc) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72518

	LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, His) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Mouse	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P75866

	LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, Fc) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Mouse	HEK293
	The LILRB4/CD85k/ILT3 protein is a multifaceted inhibitory receptor in immune regulation that significantly downregulates multiple immune responses. As a receptor for FN1 and integrin ITGAV/ITGB3, LILRB4/ILT3 inhibits IgE-mediated mast cell activation, KITLG/SCF-mediated mast cell activation, and antibody production by memory/marginal zone B cells through the ITGAV/ITGB3 interaction. LILRB4/CD85k/ILT3 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76440

	LILRB4/CD85k/ILT3 Protein, Human (Biotinylated, HEK293, His) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Human	HEK293
	The LILRB4/CD85k/ILT3 protein is a key inhibitory receptor that plays a key role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, thereby reducing TNF production. LILRB4/CD85k/ILT3 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705262

	LILRB4/CD85k/ILT3 Protein, Mouse (Biotinylated, HEK293, His-Avi) Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85k; Lilrb4; Gp49b	Mouse	HEK293

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Host:	Mouse (2)
Reactivity:	Human (2)
Application:	IHC-P (2) ICC/IF (2) FC (2) ELISA (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2) Biotin (7)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

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HY-P84679

	CD85K Antibody (YA4376) ILT3; LIR5; LILRB4; ILT-3; LIR-5	IHC-P, ICC/IF, FC, ELISA	Human
	CD85K Antibody (YA4376) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD85K. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

HY-P84679A

	CD85K Antibody (YA4376)(PBS only) ILT3; LIR5; LILRB4; ILT-3; LIR-5	IHC-P, ICC/IF, FC, ELISA	Human
	CD85K Antibody (YA4376) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD85K. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

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