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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
INS-1E
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "INS-1E" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P10769
CAS No.: 2209854-03-3
Research Areas:
1
1 Cited Publications
Synonyms: LY2608204; SY-004
Target:
Research Areas:
Globalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes [1] .
Cat. No.: HY-Y0749
CAS No.: 23150-65-4
Synonyms: Dimethyl glutamate hydrochloride
Target:
Cat. No.: HY-W037817
CAS No.: 6525-53-7
Synonyms: Dimethyl glutamate
Target:
Research Areas:
Cat. No.: HY-172786
CAS No.: 1984421-81-9
Research Areas:
Caspase-3-IN-3 (compound 7) is a caspase 3 inhibitor. Caspase-3-IN-3 increases cellular ATP levels, inhibits caspase-3 activity, decreases nitrite production, suppresses cytokine-induced apoptosis, and restores Glucose (HY-B0389)-stimulated insulin secretion [1].
Cat. No.: HY-184326
CAS No.: 3080324-43-9
Research Areas:
DRAK2-IN-2 is a selective DRAK2 inhibitor with an IC50 value of 198.5 nM. DRAK2-IN-2 inhibits DRAK2-mediated phosphorylation of ULK1 at the Ser56 site. DRAK2-IN-2 enhances insulin secretion, increases mitochondrial membrane potential, alleviates Palmitic acid (HY-N0830)-induced mitochondrial membrane potential damage and Apoptosis, and improves glucose tolerance in vivo. DRAK2-IN-2 can be used for the research of type 2 diabetes [1].
Cat. No.: HY-182832
Synonyms: Dry skim milk; Non-fat milk solids; Skimmed milk powder
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
