Skim Milk powder
Skim Milk powder (Dry skim milk) is an orally effective, dairy-derived non-fat milk solid powder. Skim Milk powder serves as a nutrient source in microbial culture media and can also be used for blocking procedures in WB assays. Skim Milk powder protects zebrafish sperm from oxidative stress, DNA damage, membrane disruption and morphological abnormalities during cryopreservation, and improves their survival rate. After undergoing high Maillard reaction during moist-heat storage, Skim Milk powder exhibits negative metabolic activities such as inhibiting GLP-1/GIP and promoting intestinal inflammation. Skim Milk powder can be used in studies related to intestinal inflammation, diabetes and obesity.
For research use only. We do not sell to patients.
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
More
Biological Activity
Description
In Vitro
Skim milk powder (15%) added to cryoprotectant solutions significantly improves post-thaw viability, membrane integrity, normal morphology, reduces oxidative stress, and minimizes DNA damage in isolated Danio rerio sperm cells[1].
Stored skim milk powder (5-25% vol/vol; 24 h) dose-dependently reduces the viability of murine intestinal neuroendocrine STC-1 cells, with a more potent effect than fresh skim milk powder at concentrations ≥15% vol/vol[3].
Stored skim milk powder (5-25% vol/vol; 24 h) dose-dependently inhibits the proliferation of murine intestinal neuroendocrine STC-1 cells, with a more potent effect than fresh skim milk powder at concentrations ≥20% vol/vol[3].
Stored skim milk powder (24 h) does not promote passage of the Maillard reactant CML across the human intestinal epithelial Caco-2 cell barrier, and basolateral medium from Caco-2 cells exposed to stored skim milk powder does not affect the viability of insulin-producing INS-1E cells[3].
Fresh skim milk powder (20-100% vol/vol; 24 h) dose-dependently stimulates GLP-1 secretion from murine intestinal neuroendocrine STC-1 cells, while stored skim milk powder fails to stimulate secretion and reduces GLP-1 release at concentrations ≥50% vol/vol[3].
Stored skim milk powder (20-100% vol/vol; 24 h) significantly reduces GIP secretion from murine intestinal neuroendocrine STC-1 cells at concentrations ≥20% vol/vol, while fresh skim milk powder supports normal GIP release[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
SMILES
[Skim milk powder]
-
Synonyms
Dry skim milk; Non-fat milk solids; Skimmed milk powder
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)