2 Results for "

ITN

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ITN" in MCE Product Catalog:

Cat. No.: HY-N17314
CAS No.: 1863020-82-9
Synonyms: (R)-ITN
(R)-Isostrictiniin ((R)-ITN) is a natural product that can be found in Burnt Sanguisorba officinalis.
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Cat. No.: HY-N17317
CAS No.: 1801746-41-7
Synonyms: ITN
Isostrictiniin (ITN) is a polyphenolic compound isolated from Nymphaea candida. It upregulates the expression of Nrf2 and HO-1, while downregulating the expression of Keap1. Isostrictiniin reduces the phosphorylation levels of JNK, ERK1/2, p38, IκBα, and NF-κB p65. Isostrictiniin decreases the levels of pro-inflammatory mediators (IL-1β, IL-6, TNF-α, PGE2). Isostrictiniin alleviates LPS-induced acute lung injury and exerts protective effects against acute alcoholic liver injury. Additionally, isostrictiniin exhibits anti-inflammatory, antioxidant, and anti-fibrotic activities.
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