20 Results for "

In-vivo

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "In-vivo" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-120394
CAS No.: 1533438-83-3
Purity:  99.69%
Research Areas:  

Cancer

TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth .
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3
3 Cited Publications
Cat. No.: HY-B1057
CAS No.: 23327-57-3
Synonyms: FenazoxIne hydrochloride
Target:  

β-catenin

Research Areas:  

Neurological Disease Cancer

Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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1
1 Cited Publications
Cat. No.: HY-P1663
CAS No.: 272121-15-0
Target:  

VEGFR

Research Areas:  

Others

ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)
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Inactive ASO (in vivo) sodium
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CCTATAGGACTATCCAGGAA
Cat. No.: HY-153734
Purity:  92.18%
Inactive ASO (in vivo) sodium is an inactive Antisense Oligonucleotide. ASO is a class of oligonucleotide molecules, usually composed of 20-30 bases, used to interfere with or regulate gene expression. Inactive ASO (in vivo) sodium is not targeted in the rodent genome and can be used as a negative control for Tofersen. Inactive ASO (in vivo) sodium contains thiophosphate skeleton modification and MOE modification. Cytosine in Inactive ASO (in vivo) is 5' methylcytosine. See References for the location of chemical modifications
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Cat. No.: HY-185039
Research Areas:  

Others

siRNA negative control (In Vivo) is a siRNA that can be used as a negative control. siRNA negative control (In Vivo) , modified with cholesterol and methoxy, can be used as a negative control in animals.
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Cat. No.: HY-B1057S1
CAS No.: 2747915-60-0
Synonyms: FenazoxIne-d4 hydrochloride
Nefopam-d4 (hydrochloride) is deuterium labeled Nefopam (hydrochloride). Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-146370
CAS No.: 2986222-50-6
Target:  

COX

Research Areas:  

Inflammation/Immunology

COX-2-IN-12 (compound 3b) is a potent and selective inhibitor of COX-2 with an IC50 of 19.98 μM. COX-2-IN-12 is an anti-inflammatory agent. COX-2-IN-12 shows safety in-vivo acute toxicity study .
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Cat. No.: HY-178994
Target:  

Flavivirus Dengue Virus

Research Areas:  

Infection

DENV-IN-14 (Compound 3c) is a thiazole hydrazone derivative with anti-dengue virus (DENV) activity with an EC50 of 0.01 μM and the selectivity index (SI) of 200. DENV-IN-14 exhibits rapid plasma clearance and its metabolic stability is limited. DENV-IN-14 can be used for research on dengue fever .
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Cat. No.: HY-175733
CAS No.: 3105591-09-8
Target:  

RIO Kinase Apoptosis

Research Areas:  

Cancer

CQ3196 is an orally active RIOK2 inhibitor with a Kd of 14 nM. CQ3196 effectively inhibits the ATPase activity of RIOK2, with an IC50 value of 72 nM. CQ3196 inhibits cell proliferation and colony formation in gastric cancer cell lines. CQ3196 induces cell apoptosis in HGC-27 and AGS cells. CQ3196 suppresses downstream signal pathway of RIOK2. CQ3196 reduces phosphorylation of mTOR and AKT. CQ3196 modulates ribosome function and protein synthesis. CQ3196 inhibits tumor growth and can be used for gastric cancer invtro and invivo research .
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Cat. No.: HY-P10821
Research Areas:  

Cardiovascular Disease

Myr-Tat-PKCβII is a cell permeable protein kinase C β II peptide inhibitor. Myr-Tat-PKCβII mitigates the generation of reactive oxygen species in rat ex-vivo and porcine in-vivo ischemia-reperfusion injury .
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Cat. No.: HY-133115
CAS No.: 46868-19-3
Target:  

β-catenin

Research Areas:  

Neurological Disease

N-Desmethylnefopam is the main metabolite of Nefopam. N-Desmethylnefopam is a centrally-acting but non-opioid analgesic agent, for the relief of moderate to severe pain. Nefopam targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-B1057S
CAS No.: 1346603-30-2
Synonyms: FenazoxIne-d3 hydrochloride
Nefopam-d3 (hydrochloride) is the deuterium labeled Nefopam hydrochloride. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-B1057R
CAS No.: 23327-57-3
Synonyms: FenazoxIne hydrochloride (Standard)
Research Areas:  

Neurological Disease Cancer

Nefopam (hydrochloride) (Standard) is the analytical standard of Nefopam (hydrochloride). This product is intended for research and analytical applications. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-W015618R
CAS No.: 89-74-7
Nefopam (hydrochloride) (Standard) is the analytical standard of Nefopam (hydrochloride). This product is intended for research and analytical applications. Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-146371
CAS No.: 2987588-45-2
Target:  

COX

Research Areas:  

Inflammation/Immunology

COX-2-IN-13 (compound 13e) is a potent and selective inhibitor of COX-2 with an IC50 of 0.98 μM. COX-2-IN-13 is an anti-inflammatory agent. COX-2-IN-13 shows safety in-vivo acute toxicity study .
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Cat. No.: HY-133115S
CAS No.: 2748500-28-7
N-Desmethylnefopam-d5 is the deuterium labeled N-Desmethylnefopam (HY-133115). N-Desmethylnefopam is the main metabolite of Nefopam. N-Desmethylnefopam is a centrally-acting but non-opioid analgesic agent, for the relief of moderate to severe pain. Nefopam targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo .
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Cat. No.: HY-169129
CAS No.: 150869-74-2
Synonyms: ILX-295501
Target:  

Drug Derivative

Research Areas:  

Cancer

LY-295501 is a sulfonylurea compound that has demonstrated in-vivo antitumor activity against a broad spectrum of solid tumors. LY-295501 can be utilized in cancer research .
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Cat. No.: HY-P702967
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: InCENP; BInds And Activates Aurora-B And -C In vivo And In Vitro; Inner Centromere ProteIn; Inner Centromere ProteIn Antigens (135kD, 155kD); Inner Centromere ProteIn Antigens 135/155kDa; Inner Centromere ProteIn InCENP; FLJ31633; Chromosomal Passenger Pr
Species:  
Source:  
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Cat. No.: HY-P87277
Synonyms: bInds and activates aurora B and C In vivo and In vitro antibody; Chromosomal passenger proteIn antibody; InCE_HUMAN antibody; InCENP antibody; Inner centromere proteIn antibody; Inner centromere proteIn antigens 135/155kDa antibody; Inner centromere proteIn antigens 135kD 155kD antibody; Inner centromere proteIn InCENP antibody

Host:  

Mouse

Application:  

ICC/IF, IHC-P, FC

Reactivity:  

Human

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Cat. No.: HY-P87277A
Synonyms: bInds and activates aurora B and C In vivo and In vitro antibody; Chromosomal passenger proteIn antibody; InCE_HUMAN antibody; InCENP antibody; Inner centromere proteIn antibody; Inner centromere proteIn antigens 135/155kDa antibody; Inner centromere proteIn antigens 135kD 155kD antibody; Inner centromere proteIn InCENP antibody

Host:  

Mouse

Application:  

ICC/IF, IHC-P, FC

Reactivity:  

Human

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