ATWLPPR Peptide
Based on 1 publication(s) in Google Scholar
ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)
For research use only. We do not sell to patients.
- Purity: 99.63%
- CAS No.: 272121-15-0
- Formula: C40H61N11O9
- Molecular Weight:839.98
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) ATWLPPR Peptide
MoreAll VEGFR Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
19 μM
Compound: ATWLPPR
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Inhibition of VEGF binding to NRP1 expressed in CHO cells
Inhibition of VEGF binding to NRP1 expressed in CHO cells
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[PMID: 20363638] |
Chemical Information
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CAS No. 272121-15-0
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Appearance Solid
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Molecular Weight 839.98
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Formula C40H61N11O9
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Color White to off-white
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Sequence
Ala-Thr-Trp-Leu-Pro-Pro-Arg
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Sequence Shortening
ATWLPPR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Adv
Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2. [Abstract]2020 Nov 25;6(48):eabc4493. PMID: 33239293
Solvent & Solubility
DMSO : 100 mg/mL (119.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (254 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1905 mL | 5.9525 mL | 11.9050 mL | 29.7626 mL |
| 5 mM | 0.2381 mL | 1.1905 mL | 2.3810 mL | 5.9525 mL | |
| 10 mM | 0.1191 mL | 0.5953 mL | 1.1905 mL | 2.9763 mL | |
| 15 mM | 0.0794 mL | 0.3968 mL | 0.7937 mL | 1.9842 mL | |
| 20 mM | 0.0595 mL | 0.2976 mL | 0.5953 mL | 1.4881 mL | |
| 25 mM | 0.0476 mL | 0.2381 mL | 0.4762 mL | 1.1905 mL | |
| 30 mM | 0.0397 mL | 0.1984 mL | 0.3968 mL | 0.9921 mL | |
| 40 mM | 0.0298 mL | 0.1488 mL | 0.2976 mL | 0.7441 mL | |
| 50 mM | 0.0238 mL | 0.1191 mL | 0.2381 mL | 0.5953 mL | |
| 60 mM | 0.0198 mL | 0.0992 mL | 0.1984 mL | 0.4960 mL | |
| 80 mM | 0.0149 mL | 0.0744 mL | 0.1488 mL | 0.3720 mL | |
| 100 mM | 0.0119 mL | 0.0595 mL | 0.1191 mL | 0.2976 mL |
ATWLPPR Peptide Related Classifications
HY-P1663 Related Classifications
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