2. Peptides
  3. ATWLPPR Peptide

ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)

For research use only. We do not sell to patients.

Custom Peptide Synthesis

ATWLPPR Peptide Chemical Structure

ATWLPPR Peptide Chemical Structure

CAS No. : 272121-15-0

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1 mg USD 50 In-stock
5 mg USD 118 In-stock
10 mg USD 177 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of ATWLPPR Peptide:

ATWLPPR Peptide Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE ATWLPPR Peptide

  • Biological Activity

  • Purity & Documentation

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Description

ATWLPPR Peptide is a biological active peptide. (This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.)

Molecular Weight

839.98

Formula

C40H61N11O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Thr-Trp-Leu-Pro-Pro-Arg
Sequence Shortening

ATWLPPR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (119.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1905 mL 5.9525 mL 11.9050 mL
5 mM 0.2381 mL 1.1905 mL 2.3810 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1905 mL 5.9525 mL 11.9050 mL 29.7626 mL
5 mM 0.2381 mL 1.1905 mL 2.3810 mL 5.9525 mL
10 mM 0.1191 mL 0.5953 mL 1.1905 mL 2.9763 mL
15 mM 0.0794 mL 0.3968 mL 0.7937 mL 1.9842 mL
20 mM 0.0595 mL 0.2976 mL 0.5953 mL 1.4881 mL
25 mM 0.0476 mL 0.2381 mL 0.4762 mL 1.1905 mL
30 mM 0.0397 mL 0.1984 mL 0.3968 mL 0.9921 mL
40 mM 0.0298 mL 0.1488 mL 0.2976 mL 0.7441 mL
50 mM 0.0238 mL 0.1191 mL 0.2381 mL 0.5953 mL
60 mM 0.0198 mL 0.0992 mL 0.1984 mL 0.4960 mL
80 mM 0.0149 mL 0.0744 mL 0.1488 mL 0.3720 mL
100 mM 0.0119 mL 0.0595 mL 0.1191 mL 0.2976 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATWLPPR Peptide272121-15-0OthersInhibitorinhibitorinhibit

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