1533438-83-3
1533438-83-3
Chemical Structure
TVB-3166
- CAS No.: 1533438-83-3
- Formula:C24H24N4O
- Molecular Weight:384.47
IUPAC Name: 4-(1-(5-(4,5-dimethyl-1H-pyrazol-3-yl)-2,4-dimethylbenzoyl)azetidin-3-yl)benzonitrile
InChIKey: ICDQFUFDAFKCAX-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C2CN(C(C3=CC(C4=NNC(C)=C4C)=C(C)C=C3C)=O)C2)C=C1
Biological Activity: TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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TVB-3166 | 99.69% | TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-U00436FASN-IN-3 -
Similarity Score 0.66
HY-120062TVB-3664 -
Similarity Score 0.58
HY-112829Denifanstat -
Similarity Score 0.46
HY-19982AKT-IN-6 -
Similarity Score 0.46
HY-171194VU0530244 -
Similarity Score 0.45
HY-184596VU6066098 -
Similarity Score 0.45
![2′,3,3′′,5′-Tetramethyl[1,1′:4′,1′′-terphenyl]-4,4′′-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w586858.gif)
HY-W5868582′,3,3′′,5′-Tetramethyl[1,1′:4′,1′′-terphenyl]-4,4′′-dicarboxylic acid -
Similarity Score 0.45
HY-145042HPK1-IN-16 -
Similarity Score 0.45
HY-162545HPK1-IN-47 -
Explore the MedChemAI to find more analogs
![2′,3,3′′,5′-Tetramethyl[1,1′:4′,1′′-terphenyl]-4,4′′-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w586858.gif)
