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Results for "

Indole moiety

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117664
    PNR-7-02

    		Reverse Transcriptase Inflammation/Immunology Cancer
    PNR-7-02 inhibits Pol η function with an IC50 value of near 8 μM, which binds to the little finger domain. PNR-7-02 is also an inhibitor against hRev1 and hpol lambda (λ). PNR-7-02 acts synergistically with Cisplatin (HY-17394) to kill chronic myeloid leukaemia and ovarian cancer cell lines. PNR-7-02 is an indole thio-barbituric acid (ITBA) derivative with both N-napthoyl moiety and 5-chloro substituent on the indole ring .
    PNR-7-02
  • HY-107767
    Antibiotic DC 81

    DC 81

    		 Antibiotic Apoptosis DNA/RNA Synthesis Cancer
    Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
    Antibiotic DC 81
  • HY-100217
    DL-3-Indolylglycine

    		Amino Acid Derivatives Others
    DL-3-Indolylglycine is an unnatural amino acid that is very similar to Tryptophan, with the indole moiety directly attached to the α-position.
    DL-3-Indolylglycine
  • HY-N3796
    Echinulin

    Echinuline

    		 NF-κB Inflammation/Immunology
    Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent .
    Echinulin
  • HY-N4173R
    8-Oxoepiberberine (Standard)

    		Reference Standards Drug Metabolite Metabolic Disease
    p-Dimethylaminobenzaldehyde (Standard) is the analytical standard of p-Dimethylaminobenzaldehyde. This product is intended for research and analytical applications. p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) is an organic compound containing amine and aldehyde moieties which is used in Ehrlich's reagent and Kovac's reagent to test for indoles .
    8-Oxoepiberberine (Standard)
  • HY-Z1146
    7-Methoxytryptamine

    		Others Others
    7-Methoxytryptamine is an indole substance. The 7-methoxytryptamine moiety can be found in a number of alkaloids, first of all in Aspidosperma type alkaloids (among others as aspidospermine, beninine, dichotamine, kopsingine, 12-methoxyvoaphylline, vobtusine), but it can be also in many other type alkaloids as crenatidine, cuanzine, vincaricine, vinervinine, and others .
    7-Methoxytryptamine
  • HY-178455
    Influenza virus-IN-10

    		Influenza Virus Infection
    Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A .
    Influenza virus-IN-10

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