19716-60-0
Chemical Structure
8-Oxoepiberberine
- CAS No.: 19716-60-0
- Formula:C20H17NO5
- Molecular Weight:351.35
IUPAC Name: 8,9-dimethoxy-11,12-dihydro-14H-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-14-one
InChIKey: PJTYPIGQKDTERS-UHFFFAOYSA-N
SMILES: O=C1N2CCC3=CC(OC)=C(OC)C=C3C2=CC4=CC=C(OCO5)C5=C14
Biological Activity: 8-Oxoepiberberine is an alkaloid metabolite in serum after oral administration of Zuojin formula. Zuojin formula is a traditional Chinese medicine used for the study of gastrointestinal diseases and consists of Coptis chinensis and Evodia rutaecarpa. 8-Oxoepiberberine is predicted to be a potential active alkaloid of Heiguteng Zhuifeng Huoluo Capsule. 8-Oxoepiberberine can be used in studies related to rheumatoid arthritis[1][2].
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8-Oxoepiberberine | 99.72% | 8-Oxoepiberberine is an alkaloid metabolite in serum after oral administration of Zuojin formula. Zuojin formula is a traditional Chinese medicine used for the study of gastrointestinal diseases and consists of Coptis chinensis and Evodia rutaecarpa. 8-Oxoepiberberine is predicted to be a potential active alkaloid of Heiguteng Zhuifeng Huoluo Capsule. 8-Oxoepiberberine can be used in studies related to rheumatoid arthritis. | ||||||||||||||||||||
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8-Oxoepiberberine (Standard) | ≥98% | 8-Oxoepiberberine (Standard) is the analytical standard of 8-Oxoepiberberine (HY-N4173). This product is intended for research and analytical applications. 8-Oxoepiberberine is an alkaloid metabolite in serum after oral administration of Zuojin formula. Zuojin formula is a traditional Chinese medicine used for the study of gastrointestinal diseases and consists of Coptis chinensis and Evodia rutaecarpa. 8-Oxoepiberberine is predicted to be a potential active alkaloid of Heiguteng Zhuifeng Huoluo Capsule. 8-Oxoepiberberine can be used in studies related to rheumatoid arthritis. | ||||||||||||||||||||
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References
- [1]. Qian P, et al. Pharmacokinetics Studies of 12 Alkaloids in Rat Plasma after Oral Administration of Zuojin and Fan-Zuojin Formulas. Molecules (Basel, Switzerland). 2017 Jan 30;22(2):214. [Content Brief]
- [2]. Mu KL, et al. Analysis of Chemical Constituents of Miao Ethnomedicine Heiguteng Zhuifeng Huoluo Capsule (HZFC) and the Discovery of Active Substances in the Treatment of Rheumatoid Arthritis. ACS omega. 2024 Mar 05;9(9):10860-10874.
