178 Results for "

Ionizable lipids

" in MedChemExpress (MCE) Product Catalog:
Products (178)

178 Results for "Ionizable lipids" in MCE Product Catalog:

168
168 Publications Verification
Cat. No.: HY-112251
CAS No.: 1224606-06-7
Purity:  99.68%
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
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20
20 Cited Publications
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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5
5 Cited Publications
Cat. No.: HY-134781
CAS No.: 1432494-65-9
Purity:  ≥98.0%
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
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3
3 Cited Publications
Cat. No.: HY-112757
CAS No.: 871258-12-7
Purity:  99.02%
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
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3
3 Cited Publications
Cat. No.: HY-130751
CAS No.: 127512-29-2
Purity:  ≥98.0%
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
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2
2 Cited Publications
Cat. No.: HY-W590532
CAS No.: 2566523-06-4
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
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2
2 Cited Publications
Cat. No.: HY-145793
CAS No.: 2328129-27-5
Purity:  ≥98.0%
FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .
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1
1 Cited Publications
Cat. No.: HY-151507
CAS No.: 2322290-93-5
Purity:  ≥98.0%
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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1
1 Cited Publications
Cat. No.: HY-153373
CAS No.: 2768211-13-6
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
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1
1 Cited Publications
Cat. No.: HY-156630
CAS No.: 2055939-68-7
Purity:  ≥98.0%
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
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1
1 Cited Publications
Cat. No.: HY-150115
CAS No.: 2430034-02-7
Purity:  ≥95.0%
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
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1
1 Cited Publications
Cat. No.: HY-112772A
CAS No.: 917572-74-8
Purity:  ≥98.0%
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
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1
1 Cited Publications
Cat. No.: HY-148855
CAS No.: 2383003-60-7
Purity:  ≥98.0%
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
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1
1 Cited Publications
Cat. No.: HY-145799
CAS No.: 1857341-90-2
Purity:  95.98%
5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
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1
1 Cited Publications
Cat. No.: HY-145799A
Purity:  98.03%
Target:  

Liposome

Research Areas:  

Cancer

5A2-SC8 TFA is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 TFA LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
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Cat. No.: HY-148842
CAS No.: 2639634-80-1
Purity:  98.13%
Synonyms: C14-494
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
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Cat. No.: HY-170333
CAS No.: 2996998-09-3
Synonyms: CICL1
Target:  

Liposome

Research Areas:  

Inflammation/Immunology

Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection .
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Cat. No.: HY-153378
CAS No.: 2588111-36-6
Purity:  ≥98.0%
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
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Cat. No.: HY-149156
CAS No.: 2767561-52-2
Purity:  99.9%
Lipid C24 is a cationic ionizable lipid that can be used for synthesizing lipid nanoparticles. Lipid C24 can be used in the study of drug delivery .
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Cat. No.: HY-147332
CAS No.: 2361162-70-9
Purity:  99.92%
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
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