2322290-93-5
Chemical Structure
306Oi10
- CAS No.: 2322290-93-5
- Formula:C59H115N3O8
- Molecular Weight:994.56
IUPAC Name: tetrakis(8-methylnonyl) 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrapropionate
InChIKey: BPPZRZOKGADTQE-UHFFFAOYSA-N
SMILES: O=C(CCN(CCCN(CCCN(CCC(OCCCCCCCC(C)C)=O)CCC(OCCCCCCCC(C)C)=O)C)CCC(OCCCCCCCC(C)C)=O)OCCCCCCCC(C)C
Biological Activity: 306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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306Oi10 | 98.07% | 306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery. | ||||||||||||||||||||
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- [1]. Hajj K A. Lipid Nanoparticle Systems for the Delivery of Messenger RNA. Carnegie Mellon University, 2019.
- [2]. Hajj KA, et al. Branched-Tail Lipid Nanoparticles Potently Deliver mRNA In Vivo due to Enhanced Ionization at Endosomal pH. Small. 2019 Feb;15(6):e1805097. doi: 10.1002/smll.201805097. [Content Brief]
Keywords
