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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
KLF5
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "KLF5" in MCE Product Catalog:
16
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1 Cited Publications
SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer .
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1 Cited Publications
Cat. No.: HY-W011044
CAS No.: 749872-43-3
CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro .
Cat. No.: HY-N1570
CAS No.: 34175-96-7
Category:
other families Ketones, Aldehydes, Acids Plants Disease Research Fields Inflammation/Immunology Pteridium aquilinum Pteridiaceae
Target:
Cat. No.: HY-RS07342
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KLF5 Human Pre-designed siRNA Set A contains three designed siRNAs for KLF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23111
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Klf5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Klf5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16676
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Klf5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klf5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N1570R
CAS No.: 34175-96-7
Cat. No.: HY-182820
CAS No.: 3086041-35-9
Target:
Research Areas:
YZ-836P is a Protein arginine methyltransferase 5 (PRMT5) targeting agent. YZ-836P promotes ubiquitination and proteasomal degradation of PRMT5 in a cereblon (CRBN)-dependent manner, which in turn reduces levels of its downstream target KLF5. YZ-836P induces G1 phase cell cycle arrest in triple-negative breast cancer cells. YZ-836P induces Apoptosis in triple-negative breast cancer cells. YZ-836P exerts cytotoxic effects on triple-negative breast cancer cells. YZ-836P inhibits the growth of triple-negative breast cancer patient-derived organoids. YZ-836P inhibits the growth of triple-negative breast cancer xenografts in nude mice. YZ-836P can be used for the research of triple-negative breast cancer .
Cat. No.: HY-P87270
Synonyms: Basic transcription element binding protein 2 antibody; Basic transcription element-binding protein 2 antibody; BTE binding protein 2 antibody; BTE-binding protein 2 antibody; BTEB 2 antibody; BTEB2 antibody; CKLF antibody; Colon krueppel like factor antibody; Colon krueppel-like factor antibody; GC box binding protein 2 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
