1. MAPK/ERK Pathway
  2. KLF
  3. CID 5951923

CID 5951923 

Cat. No.: HY-W011044
Handling Instructions

CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro.

For research use only. We do not sell to patients.

CID 5951923 Chemical Structure

CID 5951923 Chemical Structure

CAS No. : 749872-43-3

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CID 5951923 is a potent inhibitor of Krüppel-like factor 5 (KLF5), with an IC50 of 603 nM. CID 5951923 can inhibit proliferation of cancer cells in vitro[1].

IC50 & Target

IC50: 603 nM (KLF5)[1]

In Vitro

CID 5951923 (1 nM-100 μM; 48 h) inhibits proliferation of DLD-1 cells in a dose-dependent manner[1].
CID 5951923 (10 μM; 24 h) significantly decreases endogenous KLF5 levels in the DLD-1 cells, increases phosphorylation levels of pEGFFpY1068, and downregulated EGR1[1].
CID 5951923 (10 μM) inhibits proliferation of cancer cell lines mainly in highly express KLF5 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: DLD-1 and IEC-6 cells
Concentration: 0.001, 0.01, 0.1, 1, 10, 100 μM
Incubation Time: 48 h
Result: Inhibited proliferation of DLD-1 cells with an IC50 of 1.6 μM.
Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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CID 5951923CID5951923CID-5951923KLFKrüppel-like factorKrüppel-likefactor5transcriptionKLF5cancerInhibitorinhibitorinhibit

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