2505001-62-5
2505001-62-5
Chemical Structure
SR18662
- CAS No.: 2505001-62-5
- Formula:C16H19Cl2N3O4S
- Molecular Weight:420.31
IUPAC Name: (E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide
InChIKey: WUJBXFXHDUVSFM-HWKANZROSA-N
SMILES: ClC1=CC(/C=C/C(NCC(N2CCN(CC2)S(C)(=O)=O)=O)=O)=CC=C1Cl
Biological Activity: SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1].
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SR18662 | 99.61% | SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer. | ||||||||||||||||||||
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References
Keywords
