7 Results for "

Kv1.6

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Kv1.6" in MCE Product Catalog:

Cat. No.: HY-108574
CAS No.: 478341-55-8
Purity:  99.61%
Research Areas:  

Neurological Disease

CP 339818 hydrochloride is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 hydrochloride inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP 339818 hydrochloride has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP 339818 hydrochloride selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP 339818 hydrochloride can be used to study the physiological functions of HCN and Kv channels .
loading...
    loading...
Cat. No.: HY-P2707
CAS No.: 74504-53-3
Synonyms: α-DTX
Research Areas:  

Neurological Disease

α-Dendrotoxin (α-DTX) is a voltage-gated K + channel blocker and an acid-sensing ion channel (ASIC) inhibitor. α-Dendrotoxin blocks Kv1.1, Kv1.2, Kv1.6 and D-type (ID) voltage-gated K + channels, and reversibly inhibits slowly inactivating potassium currents. α-Dendrotoxin induces epilepsy-related behaviors in mice. α-Dendrotoxin can be used in studies related to tonic-clonic seizures .
loading...
    loading...
Cat. No.: HY-P3055A
Synonyms: DTX-I TFA
Target:  

Potassium Channel

Research Areas:  

Cancer

Dendrotoxin-I (DTX-I) TFA is a potent K + channel blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2 and KV1.6. Dendrotoxin-I TFA, a neurotoxin, has the potential for cancer research .
loading...
    loading...
Cat. No.: HY-P3055
CAS No.: 107950-33-4
Synonyms: DTX-I
Dendrotoxin-I (DTX-I) is a potent K + channels blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2 and KV1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .
loading...
    loading...
Cat. No.: HY-P3014
Target:  

Potassium Channel

Research Areas:  

Others

Hongotoxin-1, isolated from venom of Centruroides limbatus, is the inhibitor of potassium channel, with IC50 for? Kv1.1, Kv1.2, Kv1.3, and Kv1.6 of 31 pM, 170 pM, 86 pM,and 6000 pM, respectively .
loading...
    loading...
Cat. No.: HY-114540
CAS No.: 185855-91-8
Research Areas:  

Neurological Disease

CP-339818 is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP-339818 selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP-339818 can be used to study the physiological functions of HCN and Kv channels .
loading...
    loading...
Cat. No.: HY-RS07102
Research Areas:  

Others

KCNA6 Human Pre-designed siRNA Set A contains three designed siRNAs for KCNA6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...