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Results for "

L-BPA

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W087830
    L-p-Boronophenylalanine

    L-BPA

    		 Biochemical Assay Reagents Cancer
    L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma .
    L-p-Boronophenylalanine
  • HY-N16011
    18:1 BMP (S,S) ammonium
    1 Publications Verification

    18:1 LBPA (S,S)

    		 Biochemical Assay Reagents Others
    18:1 BMP (S,S) ammonium is a bis(monoacylglycero)phosphate (BMP).
    18:1 BMP (S,S) ammonium
  • HY-183597
    L-BPA-BPA

    		Drug Derivative Cancer
    L-BPA-BPA is an aromatic dipeptide and an analog of L-BPA (HY-W087830). L-BPA-BPA undergoes rapid hydrolytic cleavage in vivo to release the boron neutron capture agent L-BPA. L-BPA-BPA enables boron delivery to tumors; when used in combination with neutron irradiation, it also induces immunological effects including vaccine responses and abscopal tumor suppression. L-BPA-BPA can be used in the research of colon cancer and hypopharyngeal cancer .
    L-BPA-BPA
  • HY-179860
    (S,S) Bisoleoyl-lysobisphosphatidic acid

    		Others Metabolic Disease
    (S,S) Bisoleoyl-lysobisphosphatidic acid is a lysobisphosphatidic acid (LBPA). LBPA plays a role in modulating the cholesterol flux through endosomes.
    (S,S) Bisoleoyl-lysobisphosphatidic acid
  • HY-183596
    L-His-BPA

    		Drug Intermediate Cancer
    L-His-BPA is a prodrug of L-p-Boronophenylalanine (L-BPA) (HY-W087830), formed by the peptide bond linkage of L-histidine (L-His) (HY-N0832) and L-BPA. L-His-BPA is rapidly cleaved by endogenous proteases to de novo release L-BPA in the systemic circulation. When used in combination with neutron irradiation, L-His-BPA induces complete and durable tumor regression, elicits cancer vaccine responses, and produces abscopal inhibitory effects on unirradiated distant tumors. L-His-BPA can be used in studies of boron neutron capture therapy (BNCT) for relapsed/advanced solid tumors .
    L-His-BPA
  • HY-N15998
    18:1 BMP (R,R) ammonium

    18:1 LBPA (R,R)

    		 Biochemical Assay Reagents Others
    18:1 BMP (R,R) ammonium is a bis(monoacylglycero)phosphate (BMP) .
    18:1 BMP (R,R) ammonium
  • HY-183513
    L-Ala-BPA

    		FAP Cancer
    L-Ala-BPA is a boron delivery agent. L-Ala-BPA is transported into tumor cells via PEPT1/2 and LAT-1 (SLC7A5) pathways and is rapidly cleaved systemically by endogenous proteases including FAP to yield L-BPA (HY-W087830). L-Ala-BPA shows antitumor activity and can be used for the research of Boron Neutron Capture Therapy (BNCT) .
    L-Ala-BPA

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