2941355-27-5
2941355-27-5
Chemical Structure
L-Ala-BPA
- CAS No.: 2941355-27-5
- Formula:C12H17BN2O5
- Molecular Weight:280.08
InChIKey: UJFUKBWPAMLIIL-XVKPBYJWSA-N
SMILES: OB(O)C1=CC=C(C[C@H](NC([C@H](C)N)=O)C(O)=O)C=C1
Biological Activity: L-Ala-BPA is a boron delivery agent. L-Ala-BPA is transported into tumor cells via PEPT1/2 and LAT-1 (SLC7A5) pathways and is rapidly cleaved systemically by endogenous proteases including FAP to yield L-BPA (HY-W087830). L-Ala-BPA shows antitumor activity and can be used for the research of Boron Neutron Capture Therapy (BNCT)[1].
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L-Ala-BPA | L-Ala-BPA is a boron delivery agent. L-Ala-BPA is transported into tumor cells via PEPT1/2 and LAT-1 (SLC7A5) pathways and is rapidly cleaved systemically by endogenous proteases including FAP to yield L-BPA (HY-W087830). L-Ala-BPA shows antitumor activity and can be used for the research of Boron Neutron Capture Therapy (BNCT). | |||||||||||||||||||||
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References
Keywords
