5 Results for "

LIPT1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "LIPT1" in MCE Product Catalog:

Lipt1 Mouse Pre-designed siRNA Set A
Lipt1 Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS16258
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Lipt1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lipt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Lipt1 siRNA-1: 5 nmol (HPLC)
Lipt1 siRNA-2: 5 nmol (HPLC)
Lipt1 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
Lipt1 Rat Pre-designed siRNA Set A
Lipt1 Rat Pre-designed siRNA Set A
Cat. No.: HY-RS26200
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Lipt1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lipt1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

LIPT1 Human Pre-designed siRNA Set A
LIPT1 Human Pre-designed siRNA Set A
Cat. No.: HY-RS07696
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

LIPT1 Human Pre-designed siRNA Set A contains three designed siRNAs for LIPT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LIPT1 Antibody (YA6638)
LIPT1 Antibody (YA6638)
0 Images
Cat. No.: HY-P86945
Synonyms: Lipoyl amidotransferase LIPT1, mitochondrial EC:2.3.1.200 Lipoate biosynthesis protein Lipoate-protein ligase Lipoyl ligase Lipoyltransferase 1 LIPT1

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

Cuproptosis Compound Library
Cuproptosis Compound Library
0 Images
Cat. No.: HY-L133
417 compounds

Copper is an important co-factor of all biological enzymes, but if the concentration exceeds the threshold of maintaining the homeostasis mechanism, copper will lead to cytotoxicity. This death mechanism has been named "Cuproptosis".

The mechanism of cuproptosis distinct from all other known mechanisms of regulated cell death, including apoptosis, pyroptosis, necroptosis, and ferroptosis.

Copper combine with the lipoylated components of the tricarboxylic acid cycle (TCA), leading to lipoylated protein aggregation and subsequent loss of iron-sulfur cluster proteins, ultimately resulting in protein toxicity stress and cell death. Studies have shown that the necessary factors for cuproptosis include the presence of glutathione, mitochondrial metabolism of galactose and pyruvate, and glutamine metabolism.

Targeted regulation of cuproptosis is a potential choice to treat cancer, rheumatoid arthritis, and other diseases. For example, up-regulation of LIPT1 may inhibit the occurrence and development of tumors by destroying TCA in mitochondria and then inducing cuproptosis.

MCE supplies a unique collection of 417 cuproptosis-related compounds, all of which act on the targets or signaling pathways related to cuproptosis and may have in inhibitory or activated effect on cuproptosis. MCE Cuproptosis Library is a useful tool for drug research related to cancer, rheumatoid arthritis, and other diseases.

Assay Types