1 Result for "

LSD1-IN-34

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LSD1-IN-34" in MCE Product Catalog:

Cat. No.: HY-162729
CAS No.: 3048029-74-6
LSD1-IN-34 (Compound 7d) is the orally active inhibitor for Lysine-specific demethylase (LSD) and monoamine oxidase (MAO), with IC50 of 4.51 and 18.46 nM, for LSD1 and MAO A. LSD1-IN-34 inhibits the Ang II-induced neonatal rat myocardial fibroblasts (NRCFs) activation, without significant toxicity (20 μM). LSD1-IN-34 inhibits TGFβ/Smad signaling pathway, and ameliorates heart failure in mice. LSD1-IN-34 exhibits good pharmacokinetic characteristics in rats .
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