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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Lipid C2
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Lipid C2" in MCE Product Catalog:
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Research Areas:
C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss .
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Cat. No.: HY-114293S
Purity: 97.40%
Synonyms: Acetyl-CoA-13C2 lithium
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β-Alanine, N,N-dimethyl-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Synonyms: DLin-M-C2-DMA
Cat. No.: HY-176518
CAS No.: 2247153-41-7
Target:
Research Areas:
ssPalmE-P4-C2 is a SS-cleavable and pH-sensitive lipid-like material (ssPalm) with a vitamin E‑scaffold. ssPalmE-P4-C2 improves gene knockdown activity against FVII with an ED50 of 0.5 mg/kg. ssPalmE-P4-C2 can be used to synthesize lipid nanoparticles (LNPs) for delivering siRNA to the hepatocyte. ssPalmE-P4-C2 can be used for the RNA therapies for dyslipidemia, hepatitis B/C infections and transthyretin amyloidosis research .
Cat. No.: HY-169480
CAS No.: 3003022-09-8
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
Cat. No.: HY-N7521
CAS No.: 37064-31-6
Synonyms: Procyanidine C2
Cat. No.: HY-153371
CAS No.: 1853203-01-6
Cat. No.: HY-N15984
CAS No.: 2260669-99-4
Cat. No.: HY-13417S
CAS No.: 1609374-70-0
Synonyms: Acadesine-13C2,15N; AICA Riboside-13C2,15N
Cat. No.: HY-W440881A
Target:
DSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research .
Cat. No.: HY-W010452S2
CAS No.: 287389-35-9
Synonyms: β-Hydroxybutyric acid-13C2 sodium
Cat. No.: HY-W747751
Cat. No.: HY-N3686S2
Cat. No.: HY-N9484S
CAS No.: 3028870-62-1
Cat. No.: HY-N16330
CAS No.: 3091879-57-8
Category:
Target:
Cat. No.: HY-178721
CAS No.: 2768690-22-6
Research Areas:
Lithocholic amide-C2-N(didecane) (Compound LC10) is a Lithocholic acid (HY-B0172) analogue. Lithocholic amide-C2-N(didecane) can form lipid nanoparticles spontaneously in the aqueous milieu, permeate through the skin, penetrate the deeper dermal layers, and exert anti-inflammatory effects against psoriasis-like chronic skin inflammations. Lithocholic amide-C2-N(didecane) can inhibit abnormal proliferation of keratinocytes, downregulate the mRNA expression of the psoriasis-associated receptor EphA2 and reduce serum levels of multiple pro-inflammatory factors such as IL-1α, IL-1β, and IFN-γ by inhibiting activation of the Th17/Th2 inflammatory pathway .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
