Lithocholic amide-C2-N(didecane)
Lithocholic amide-C2-N(didecane) (Compound LC10) is a Lithocholic acid (HY-B0172) analogue. Lithocholic amide-C2-N(didecane) can form lipid nanoparticles spontaneously in the aqueous milieu, permeate through the skin, penetrate the deeper dermal layers, and exert anti-inflammatory effects against psoriasis-like chronic skin inflammations. Lithocholic amide-C2-N(didecane) can inhibit abnormal proliferation of keratinocytes, downregulate the mRNA expression of the psoriasis-associated receptor EphA2 and reduce serum levels of multiple pro-inflammatory factors such as IL-1α, IL-1β, and IFN-γ by inhibiting activation of the Th17/Th2 inflammatory pathway.
For research use only. We do not sell to patients.
- CAS No.: 2768690-22-6
- Formula: C46H86N2O2
- Molecular Weight:699.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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EPHA2 |
IL-1α |
IL-1β |
Chemical Information
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CAS No. 2768690-22-6
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Molecular Weight 699.19
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Formula C46H86N2O2
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCN(CCCCCCCCCC)CCCCCCCCCC)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lithocholic amide-C2-N(didecane) Related Classifications
HY-178721 Related Classifications
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