ssPalmE-P4-C2
Based on 1 Customer Validation
ssPalmE-P4-C2 is a SS-cleavable and pH-sensitive lipid-like material (ssPalm) with a vitamin E‑scaffold. ssPalmE-P4-C2 improves gene knockdown activity against FVII with an ED50 of 0.5 mg/kg. ssPalmE-P4-C2 can be used to synthesize lipid nanoparticles (LNPs) for delivering siRNA to the hepatocyte. ssPalmE-P4-C2 can be used for the RNA therapies for dyslipidemia, hepatitis B/C infections and transthyretin amyloidosis research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98.81%
- CAS No.: 2247153-41-7
- Formule: C84H140N2O10S2
- Masse moléculaire:1402.15
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Stockage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Activité biologique
Description
Chemical Information
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CAS No. 2247153-41-7
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Appearance Oil
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Masse moléculaire 1402.15
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Formule C84H140N2O10S2
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Color Colorless to light yellow
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SMILES
O=C(CCC(OCCC1CCN(CC1)CCSSCCN2CCC(CC2)CCOC(CCC(OC3=C(C)C4=C(OC(CC4)(CCCC(CCCC(CCCC(C)C)C)C)C)C(C)=C3C)=O)=O)=O)OC5=C(C)C6=C(OC(CC6)(CCCC(CCCC(CCCC(C)C)C)C)C)C(C)=C5C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvant et solubilité
In Vitro:
Ethanol : ≥ 100 mg/mL (71.32 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 0.7132 mL | 3.5660 mL | 7.1319 mL | 17.8298 mL |
| 5 mM | 0.1426 mL | 0.7132 mL | 1.4264 mL | 3.5660 mL | |
| 10 mM | 0.0713 mL | 0.3566 mL | 0.7132 mL | 1.7830 mL | |
| 15 mM | 0.0475 mL | 0.2377 mL | 0.4755 mL | 1.1887 mL | |
| 20 mM | 0.0357 mL | 0.1783 mL | 0.3566 mL | 0.8915 mL | |
| 25 mM | 0.0285 mL | 0.1426 mL | 0.2853 mL | 0.7132 mL | |
| 30 mM | 0.0238 mL | 0.1189 mL | 0.2377 mL | 0.5943 mL | |
| 40 mM | 0.0178 mL | 0.0891 mL | 0.1783 mL | 0.4457 mL | |
| 50 mM | 0.0143 mL | 0.0713 mL | 0.1426 mL | 0.3566 mL | |
| 60 mM | 0.0119 mL | 0.0594 mL | 0.1189 mL | 0.2972 mL |