ssPalmE-P4-C2
Based on 1 Customer Validation
ssPalmE-P4-C2 is a SS-cleavable and pH-sensitive lipid-like material (ssPalm) with a vitamin E‑scaffold. ssPalmE-P4-C2 improves gene knockdown activity against FVII with an ED50 of 0.5 mg/kg. ssPalmE-P4-C2 can be used to synthesize lipid nanoparticles (LNPs) for delivering siRNA to the hepatocyte. ssPalmE-P4-C2 can be used for the RNA therapies for dyslipidemia, hepatitis B/C infections and transthyretin amyloidosis research.
For research use only. We do not sell to patients.
- Purity: 98.81%
- CAS No.: 2247153-41-7
- Formula: C84H140N2O10S2
- Molecular Weight:1402.15
-
Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 2247153-41-7
-
Appearance Oil
-
Molecular Weight 1402.15
-
Formula C84H140N2O10S2
-
Color Colorless to light yellow
-
SMILES
O=C(CCC(OCCC1CCN(CC1)CCSSCCN2CCC(CC2)CCOC(CCC(OC3=C(C)C4=C(OC(CC4)(CCCC(CCCC(CCCC(C)C)C)C)C)C(C)=C3C)=O)=O)=O)OC5=C(C)C6=C(OC(CC6)(CCCC(CCCC(CCCC(C)C)C)C)C)C(C)=C5C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 40 mg/mL (28.53 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7132 mL | 3.5660 mL | 7.1319 mL | 17.8298 mL |
| 5 mM | 0.1426 mL | 0.7132 mL | 1.4264 mL | 3.5660 mL | |
| 10 mM | 0.0713 mL | 0.3566 mL | 0.7132 mL | 1.7830 mL | |
| 15 mM | 0.0475 mL | 0.2377 mL | 0.4755 mL | 1.1887 mL | |
| 20 mM | 0.0357 mL | 0.1783 mL | 0.3566 mL | 0.8915 mL | |
| 25 mM | 0.0285 mL | 0.1426 mL | 0.2853 mL | 0.7132 mL |
ssPalmE-P4-C2 Related Classifications
HY-176518 Related Classifications
Powered by Bioz