2 Results for "

Lotusine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Lotusine" in MCE Product Catalog:

Lotusine
Lotusine
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Cat. No.: HY-N4309
CAS No.: 6871-67-6
Category:  

Cardiovascular Disease Alkaloids other families Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Amylases Glycosidase

Lotusine is an orally active signaling pathway modulator and enzyme inhibitor, with an IC50 of 30.60 μg/mL against α-amylase and an IC50 of 36.15 μg/mL against α-glucosidase. Lotusine inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine induces apoptosis, triggers G0/G1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder .
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Lotusine hydroxide
Lotusine hydroxide
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Cat. No.: HY-N4309A
CAS No.: 3721-76-4
Category:  

Cardiovascular Disease Alkaloids Phenols Polyphenols Nelumbo nucifera Gaertn. Plants Disease Research Fields Isoquinoline Alkaloids Nymphaeaceae

Target:  

Amylases Glycosidase

Lotusine hydroxide is an orally active signaling pathway modulator and enzyme inhibitor, with an IC50 of 30.60 μg/mL against α-amylase and an IC50 of 36.15 μg/mL against α-glucosidase. Lotusine hydroxide inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine hydroxide induces apoptosis, triggers G0/G1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine hydroxide reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine hydroxide is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder .
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