4 Results for "

MEP pathway

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "MEP pathway" in MCE Product Catalog:

Cat. No.: HY-157840
CAS No.: 758689-17-7
Target:  

Parasite

Research Areas:  

Infection

Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC50=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS) .
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Cat. No.: HY-N9923
CAS No.: 206440-72-4
2-C-Methyl-D-erythritol 4-phosphate is a metabolite intermediate exclusive to the non-mevalonate MEP pathway, predominantly found in prokaryotes, serving as a precursor for the synthesis of isoprenoids and non-isoprenoids, including vitamins; its absence in humans makes it a promising target for the development of bacterium-specific drugs aimed at treating infectious diseases.
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Cat. No.: HY-158818
CAS No.: 2260608-07-7
Target:  

Parasite

Research Areas:  

Infection

DXR-IN-2 is a 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) inhibitor and an antimalarial agent (IC50: 0.1062 μM for Plasmodium falciparum DXR and 0.369 μM for Plasmodium falciparum). DXR-IN-2 inhibits Plasmodium falciparum growth by suppressing the methyl erythritol phosphate (MEP) pathway via DXR .
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Cat. No.: HY-184985
CAS No.: 2304464-44-4
Research Areas:  

Others

DXPS-IN-3 is a Herbicide. DXPS-IN-3 inhibits DXPS (Kd = 27.2 μM) and blocks the methylerythritol phosphate (MEP) pathway. DXPS-IN-3 induces plant bleaching and death via ROS accumulation, causing chlorophyll degradation and disrupting carotenoid biosynthesis. DXPS-IN-3 exhibits activity against Descurainia sophia and other dicot weeds, and can be used in research related to farmland weed control .
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