758689-17-7
Chemical Structure
Anti-infective agent 9
- CAS No.: 758689-17-7
- Formula:C14H11F3N4S2
- Molecular Weight:356.39
InChIKey: ZBWCLPCSGPKWDG-UHFFFAOYSA-N
SMILES: CC1=C(SC(N)=N1)C2=CSC(NC3=CC=C(C=C3)C(F)(F)F)=N2
Biological Activity: Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC50=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS)[1].
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Anti-infective agent 9 | Anti-infective agent 9 (compound 1) is a Plasmodium falciparum inhibitor (IC50=600 nM), can downregulate pyruvate levels and TCA cycle in Plasmodium. Anti-infective agent 9It has good metabolic stability and low toxicity to human liver cells. The study found, Anti-infective agent 9Potential targets for inhibiting Plasmodium falciparum are not 1-deoxidation-d-xylulose-5-Phosphate synthase (DXPS). | |||||||||||||||||||||
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Keywords
