16 Results for "

Mincle

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "Mincle" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P5524A
Synonyms: Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid hydrochloride; γ-D-glutamyl-meso-diaminopimelic acid hydrochloride
C12-iE-DAP hydrochloride (Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid HYdrochloride) is a highly potent and selective NOD1 agonist, with an EC50 of 0.027 nM in HEK-Blue cells expressing human NOD1. C12-iE-DAP hydrochloride activates the NOD1/RIPK2 signaling pathway and its downstream p38 MAPK and NF-κB, induces the expression of inflammatory mediators such as IL6 and IL8, and exerts synergistic effects with TLR4, Dectin-1 or Mincle signaling. C12-iE-DAP hydrochloride can be used in studies related to vascular inflammation, tumor metastasis and neuroinflammation .
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Cat. No.: HY-N10634
CAS No.: 74365-77-8
Synonyms: C16 Glucosyl(β) Ceramide (d18:1/16:0)
D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl (β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand with immunostimulatory activity. D-Glucosyl-β-1,1′-N-palmitoylsphingosine binds to and activates macrophage-inducible C-type lectin (Mincle). D-Glucosyl-β-1,1′-N-palmitoylsphingosine is applicable to the research of immune system diseases .
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Cat. No.: HY-112137
CAS No.: 66758-35-8
Purity:  99.92%
Trehalose-6,6'-dibehenate is an orally active glycolipid. Trehalose-6,6'-dibehenate activates Mincle and inflammasome, inducing IL-1β secretion in a caspase activity-dependent manner. Trehalose-6,6'-dibehenate exerts a Myd88-dependent adjuvant activity. Trehalose-6,6'-dibehenate induces Th-1/Th-17 immune responses .
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Cat. No.: HY-RS02794
Research Areas:  

Others

CLEC4E Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC4E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17848
Research Areas:  

Others

Clec4e Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clec4e gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P5524
CAS No.: 1269619-57-9
Synonyms: Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid; γ-D-glutamyl-meso-diaminopimelic acid
C12-iE-DAP (Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid) is a highly potent and selective NOD1 agonist, with an EC50 of 0.027 nM in HEK-Blue cells expressing human NOD1. C12-iE-DAP activates the NOD1/RIPK2 signaling pathway and its downstream p38 MAPK and NF-κB, induces the expression of inflammatory mediators such as IL6 and IL8, and exerts synergistic effects with TLR4, Dectin-1 or Mincle signaling. C12-iE-DAP can be used in studies related to vascular inflammation, tumor metastasis and neuroinflammation .
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Cat. No.: HY-163674
Mincle agonist 1 (compound 1c) is a Mincle agonist. Mincle agonist 1 can promote IL-1β expression in BMDM cells. Mincle agonist 1 can be used in immune and inflammation related research .
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Cat. No.: HY-RS24316
Research Areas:  

Others

Clec4e Rat Pre-designed siRNA Set A contains three designed siRNAs for Clec4e gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P77336A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-Type Lectin Domain Family 4 Member E; CLECSF9; Mincle
Species:  
Source:  
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Cat. No.: HY-P77336
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: C-Type Lectin Domain Family 4 Member E; CLECSF9; Mincle
Species:  
Source:  
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Cat. No.: HY-P70118
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuC-Type Lectin Domain Family 4 Member E/CLEC4E, His; C-Type Lectin Domain Family 4 Member E; C-Type Lectin Superfamily Member 9; Macrophage-Inducible C-Type Lectin; CLEC4E; CLECSF9; Mincle
Species:  
Source:  
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Cat. No.: HY-P706180
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-type lectin domain family 4 member E; Clec4e; C-type lectin superfamily member 9; Macrophage-inducible C-type lectin; Mincle; Clecsf9; C-type Lectin Domain Family 4, Member E
Species:  
Source:  
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Cat. No.: HY-P88322
Synonyms: CLECSF9; Mincle

Host:  

Mouse

Application:  

WB, IHC-P, FC

Reactivity:  

Human

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Cat. No.: HY-P88322A
Synonyms: CLECSF9; Mincle

Host:  

Mouse

Application:  

WB, IHC-P, FC

Reactivity:  

Human

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Cat. No.: HY-152940
CAS No.: 887907-50-8
Synonyms: C24:1 β-glucosylceramide
βGlcCer is a glycosphingolipid. βGlcCer directly increases the development and PKCα and PKCδ activation in mouse bone marrow-derived DCs (BMDCs) . β-GlcCer accumulating in Gaucher disease activates microglia through macrophage-inducible C-type lectin (Mincle) to induce phagocytosis of living neurons, which exacerbates Gaucher symptoms .
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Cat. No.: HY-N10634S
CAS No.: 71924-12-4
Synonyms: N-ω-CD3-Hexadecaoyl-glucopsychosie; GluCe(d18:1/16:0-d3); Glucosylceamide-d3 (d18:1/16:0-d3)
D-Glucosyl-β-N-palmitoylsphingosine-d3 (N-ω-CD3-Hexadecaoyl-glucopsychosie) is deuterium labeled D-Glucosyl-β-1,1′-N-palmitoylsphingosine (HY-N10634). D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand possessing immunostimulatory activity .
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